Seedings results comparison

Key Investigators

• Harvard Medical School: Antonin Perrot-Audet, Kishore Mosaliganti, Sean Megason
• RPI: Badri Roysam, Raghav Padmanabhan

Project

Objective

• Improve segmentation algorithms initialization for nuclei detection in 3D fluorescent microscopy:
  • get a better accuracy,
  • improve computation speed.

Approach, Plan

• Compare different algorithms,
• Find a measure to evaluate different algorithm results,
• Fusion output of several algorithms.

Progress

• Implemented 3 different algorithms with ITK:
  • Tensor voting,
  • Hough transform,
  • Multi-scale Distance Map weighted Laplacian of Gaussian.