2008 Summer Project Week:FluidMechanicsTractographyUCLA - Revision history

Nhageman: /* Key Investigators */

2008-06-26T23:58:58Z

Key Investigators

2008-06-23T17:35:05Z

Key Investigators

2008-06-23T17:33:41Z

Key Investigators

2008-06-23T16:00:06Z

Key Investigators

2008-06-23T15:55:49Z

Key Investigators

2008-06-23T15:55:23Z

Key Investigators

2008-06-23T15:38:10Z

2008-06-23T15:35:49Z

2008-06-23T15:35:15Z

2008-06-23T15:34:11Z

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 **computation of fluid velocity vector field volume
 **reconstruction of tracts based on the above fluid velocity volume
-** Optimizing initial coding of method in itk (better use of multithreading)
+** Optimizing initial coding of method in ITK (better use of multithreading)
 ** Specialized visualization using VTK:
 *** Fluid velocity vector field animation
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 <h1>Progress</h1>
 </div>

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 We have developed and initially validated a DTI tractography method based on Navier-Stokes fluid mechanics.  See the papers listed in the reference section for complete details on the method.  Our approach for this project week will focus on the following:
 * Building the our current CL Slicer module into an interactive GUI in Slicer 3.  Our method is currently integrated as a CL Slicer module in a custom build of Slicer 3.  The module has the following functionalities:
-**reconstruction of the diffusion tensor and computation of common DTI scalar volumes (FA, LI, RGB)
+**reconstruction of the diffusion tensor and computation of common DTI scalar volumes (FA, LI, RGB).  In addition, if users prefer using their own tensor reconstruction methods, the module can be run with any arbitrary set of tensor volumes.
 **computation of fluid velocity vector field volume
 **reconstruction of tracts based on the above fluid velocity volume
 ** Optimizing initial coding of method in itk (better use of multithreading)
 ** Specialized visualization using VTK:
@@ Line 42: / Line 41: @@
 <h1>Progress</h1>
 </div>

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 <h1>Approach, Plan</h1>
 We have developed and initially validated a DTI tractography method based on Navier-Stokes fluid mechanics.  See the papers listed in the reference section for complete details on the method.  Our approach for this project week will focus on the following:
-* Building the our current CL Slicer module into an interactive GUI in Slicer 3.
+* Building the our current CL Slicer module into an interactive GUI in Slicer 3.  Our method is currently integrated as a CL Slicer module in a custom build of Slicer 3.  The module has the following functionalities:
 * Working with the interested groups in analyzing control and white matter pathology data.  Specifically, we have seen promising results when looking at the flow perturbation around white matter lesions seen in multiple sclerosis or stroke that may suggest a novel method for automatic lesion detection in DTI.
 </div>

@@ Line 27: / Line 27: @@
 We have developed and initially validated a DTI tractography method based on Navier-Stokes fluid mechanics.  See the papers listed in the reference section for complete details on the method.  Our approach for this project week will focus on the following:
 * Building the our current CL Slicer module into an interactive GUI in Slicer 3.
-* Working with the interested groups in analyzing control and white matter pathology data.
+* Working with the interested groups in analyzing control and white matter pathology data.  Specifically, we have seen promising results when looking at the flow perturbation around white matter lesions seen in multiple sclerosis or stroke that may suggest a novel method for automatic lesion detection in DTI.
 </div>

@@ Line 43: / Line 43: @@
 * Integration of method into a custom Slicer 3 GUI
 ** Optimizing initial coding of method in itk (better use of multithreading)
-** Specialized Visualization using VTK:
+** Specialized visualization using VTK:
 *** Fluid velocity vector field animation
 *** Layout for Slicer 3 Plug-in

@@ Line 41: / Line 41: @@
 Current work is focusing on optimizing the code for the above modules and integrating them as full interactive GUIs in Slicer3 software environment.  Specifically, we are working on the following aspects:
-* Integration of method into Slicer 3
+* Integration of method into a custom Slicer 3 GUI
-** Finished initial coding of method in itk
+** Optimizing initial coding of method in itk (better use of multithreading)
-** Continuing work on the following features:
+** Specialized Visualization using VTK:
 *** Fluid velocity vector field animation
 *** Layout for Slicer 3 Plug-in
+*** Interactive (real-time) manipulation of sources/sinks (ROIs) on steady-state fluid solution (possible application for intra-operative DTI)
 </div>
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 </div>
 ===References===