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	<title>2008 Winter Project Week BSplineReg - Revision history</title>
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		<id>https://www.na-mic.org/w/index.php?title=2008_Winter_Project_Week_BSplineReg&amp;diff=21195&amp;oldid=prev</id>
		<title>Serdar at 15:18, 11 January 2008</title>
		<link rel="alternate" type="text/html" href="https://www.na-mic.org/w/index.php?title=2008_Winter_Project_Week_BSplineReg&amp;diff=21195&amp;oldid=prev"/>
		<updated>2008-01-11T15:18:54Z</updated>

		<summary type="html">&lt;p&gt;&lt;/p&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #222; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #222; text-align: center;&quot;&gt;Revision as of 15:18, 11 January 2008&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l1&quot; &gt;Line 1:&lt;/td&gt;
&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 1:&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;{|&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;{|&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;|[[Image:NAMIC-SLC.jpg|thumb|320px|Return to [[2008_Winter_Project_Week]] ]]&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;|[[Image:NAMIC-SLC.jpg|thumb|320px|Return to [[2008_Winter_Project_Week]] ]]&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt;−&lt;/td&gt;&lt;td style=&quot;color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;|valign=&amp;quot;top&amp;quot;|   [[Image:&lt;del class=&quot;diffchange diffchange-inline&quot;&gt;GroupwiseStackBiModal&lt;/del&gt;.&lt;del class=&quot;diffchange diffchange-inline&quot;&gt;PNG&lt;/del&gt;|thumb|350px|Figure &lt;del class=&quot;diffchange diffchange-inline&quot;&gt;1&lt;/del&gt;: &lt;del class=&quot;diffchange diffchange-inline&quot;&gt;On the left is shown a stack of images &lt;/del&gt;&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt;+&lt;/td&gt;&lt;td style=&quot;color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;|valign=&amp;quot;top&amp;quot;|    &lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt;−&lt;/td&gt;&lt;td style=&quot;color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;del class=&quot;diffchange diffchange-inline&quot;&gt;and a sample pixel stack around a cortical region&lt;/del&gt;. &lt;del class=&quot;diffchange diffchange-inline&quot;&gt;On &lt;/del&gt;the &lt;del class=&quot;diffchange diffchange-inline&quot;&gt;left &lt;/del&gt;is &lt;del class=&quot;diffchange diffchange-inline&quot;&gt;shown &lt;/del&gt;the &lt;del class=&quot;diffchange diffchange-inline&quot;&gt;Gaussian(blue) fittet to &lt;/del&gt;&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt;+&lt;/td&gt;&lt;td style=&quot;color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;[[Image:&lt;ins class=&quot;diffchange diffchange-inline&quot;&gt;GroupwiseBspline&lt;/ins&gt;.&lt;ins class=&quot;diffchange diffchange-inline&quot;&gt;png&lt;/ins&gt;|thumb|350px|Figure &lt;ins class=&quot;diffchange diffchange-inline&quot;&gt;2&lt;/ins&gt;: &lt;ins class=&quot;diffchange diffchange-inline&quot;&gt;An example deformation field&lt;/ins&gt;. &lt;ins class=&quot;diffchange diffchange-inline&quot;&gt;The local neighborhood affecting &lt;/ins&gt;the &lt;ins class=&quot;diffchange diffchange-inline&quot;&gt;deformation &lt;/ins&gt;is &lt;ins class=&quot;diffchange diffchange-inline&quot;&gt;overlayed on &lt;/ins&gt;the &lt;ins class=&quot;diffchange diffchange-inline&quot;&gt;image&lt;/ins&gt;.]]&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt;−&lt;/td&gt;&lt;td style=&quot;color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;del class=&quot;diffchange diffchange-inline&quot;&gt;a real sample from the dataset we used along with the non-parametric density estimate(red). &lt;/del&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan=&quot;2&quot;&gt; &lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt;−&lt;/td&gt;&lt;td style=&quot;color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;del class=&quot;diffchange diffchange-inline&quot;&gt;Note that the distribution is bi-modal because of white matter-gray matter transaction&lt;/del&gt;.]]&lt;/div&gt;&lt;/td&gt;&lt;td colspan=&quot;2&quot;&gt; &lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;|}&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;|}&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;/table&gt;</summary>
		<author><name>Serdar</name></author>
		
	</entry>
	<entry>
		<id>https://www.na-mic.org/w/index.php?title=2008_Winter_Project_Week_BSplineReg&amp;diff=21193&amp;oldid=prev</id>
		<title>Serdar: New page: {| |Return to [[2008_Winter_Project_Week ]] |valign=&quot;top&quot;|   [[Image:GroupwiseStackBiModal.PNG|thumb|350px|Figure 1: On the left is shown a stack of ima...</title>
		<link rel="alternate" type="text/html" href="https://www.na-mic.org/w/index.php?title=2008_Winter_Project_Week_BSplineReg&amp;diff=21193&amp;oldid=prev"/>
		<updated>2008-01-11T15:16:45Z</updated>

		<summary type="html">&lt;p&gt;New page: {| |&lt;a href=&quot;/wiki/File:NAMIC-SLC.jpg&quot; title=&quot;File:NAMIC-SLC.jpg&quot;&gt;thumb|320px|Return to [[2008_Winter_Project_Week&lt;/a&gt; ]] |valign=&amp;quot;top&amp;quot;|   [[Image:GroupwiseStackBiModal.PNG|thumb|350px|Figure 1: On the left is shown a stack of ima...&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;{|&lt;br /&gt;
|[[Image:NAMIC-SLC.jpg|thumb|320px|Return to [[2008_Winter_Project_Week]] ]]&lt;br /&gt;
|valign=&amp;quot;top&amp;quot;|   [[Image:GroupwiseStackBiModal.PNG|thumb|350px|Figure 1: On the left is shown a stack of images &lt;br /&gt;
and a sample pixel stack around a cortical region. On the left is shown the Gaussian(blue) fittet to &lt;br /&gt;
a real sample from the dataset we used along with the non-parametric density estimate(red). &lt;br /&gt;
Note that the distribution is bi-modal because of white matter-gray matter transaction.]]&lt;br /&gt;
|}&lt;br /&gt;
&lt;br /&gt;
__NOTOC__&lt;br /&gt;
===Key Investigators===&lt;br /&gt;
* MIT: Serdar Balci, Polina Golland&lt;br /&gt;
* Kitware: Luis Ibanez&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&amp;lt;div style=&amp;quot;margin: 20px;&amp;quot;&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&amp;lt;div style=&amp;quot;width: 27%; float: left; padding-right: 3%;&amp;quot;&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&amp;lt;h1&amp;gt;Objective&amp;lt;/h1&amp;gt;&lt;br /&gt;
&lt;br /&gt;
The goal of this project is to develop an efficient B-Splines based registration code.&lt;br /&gt;
We explore the space of different optimization schemes e.g. caching, sparsity and memory-speed trade-off's.&lt;br /&gt;
&lt;br /&gt;
&amp;lt;/div&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&amp;lt;div style=&amp;quot;width: 27%; float: left; padding-right: 3%;&amp;quot;&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&amp;lt;h1&amp;gt;Approach, Plan &amp;lt;/h1&amp;gt;&lt;br /&gt;
&lt;br /&gt;
We run benchmark experiments in the special case of itkMattesMutualInformation implementation. &lt;br /&gt;
The current implementation in ITK uses caching of B-Spline coefficient in order to speed-up &lt;br /&gt;
the registration. Also the sparsity of B-Spline coefficient updates are taken into account, yielding &lt;br /&gt;
and efficient implementation.&lt;br /&gt;
&lt;br /&gt;
The drawback of caching is the use of high amounts of memory. &lt;br /&gt;
We compare the performance of caching vs. not-caching(computing the coefficients on the fly)&lt;br /&gt;
by deactivating caching code in itkMattesMutualInformation .&lt;br /&gt;
&lt;br /&gt;
&amp;lt;/div&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&amp;lt;div style=&amp;quot;width: 40%; float: left;&amp;quot;&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&amp;lt;h1&amp;gt;Progress&amp;lt;/h1&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
====Jan 2008 Project Week====&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
We run an experiment on a machine&lt;br /&gt;
with 8GB of memory, 4 core CPU &lt;br /&gt;
running gcc compiler on a linux system. &lt;br /&gt;
&lt;br /&gt;
We used a B-Spline with mesh size 32x32x16&lt;br /&gt;
with an image of size 256x256x124 and used&lt;br /&gt;
Mattes mutual information as the registration algorithm.&lt;br /&gt;
&lt;br /&gt;
Run-times:&lt;br /&gt;
* 21 seconds with caching (2.4 GB of memory)&lt;br /&gt;
* 52 seconds w/o caching (800MB of memory)&lt;br /&gt;
&lt;br /&gt;
Overall in this experiment, caching improved the performance by 2.5 while using 3 times more memory.&lt;br /&gt;
We are in the process of exploring the effect of number of samples, image size and compiler on &lt;br /&gt;
registration time.&lt;br /&gt;
&lt;br /&gt;
&amp;lt;/div&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&amp;lt;br style=&amp;quot;clear: both;&amp;quot; /&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&amp;lt;/div&amp;gt;&lt;/div&gt;</summary>
		<author><name>Serdar</name></author>
		
	</entry>
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