2010 Summer Project Week HandN Cancer - Revision history

MartaPeroni at 12:51, 25 June 2010

2010-06-25T12:51:06Z

MartaPeroni at 17:12, 21 June 2010

2010-06-21T17:12:51Z

Tkapur at 00:30, 16 June 2010

2010-06-16T00:30:08Z

MartaPeroni at 22:46, 15 June 2010

2010-06-15T22:46:53Z

MartaPeroni at 22:08, 15 June 2010

2010-06-15T22:08:53Z

MartaPeroni at 22:01, 15 June 2010

2010-06-15T22:01:28Z

MartaPeroni: Created page with 'NOTOC Image:PW-MIT2010.png|Projects List Image:genuFAp.jpg|Scatter plot of the original FA data through the genu of the corpus…'

2010-05-11T23:42:47Z

Created page with '__NOTOC__ <gallery> Image:PW-MIT2010.png|Projects List Image:genuFAp.jpg|Scatter plot of the original FA data through the genu of the corpus…'

New page

__NOTOC__
<gallery>
Image:PW-MIT2010.png|[[2010_Summer_Project_Week#Projects|Projects List]]
Image:genuFAp.jpg|Scatter plot of the original FA data through the genu of the corpus callosum of a normal brain.
Image:genuFA.jpg|Regression of FA data; solid line represents the mean and dotted lines the standard deviation.
</gallery>

==Key Investigators==
* Politecnico di Milano / MIT : Marta Peroni
* MIT: Polina Golland
* MGH: Greg Sharp

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<h3>Objective</h3>
The project aims at allowing plan adaptation throughout the treatment course by means of CBCT. This imaging technique is at its early stage in radio– and proton-therapy application and it is not yet considered a reliable tool for planning.
We would like to use Deformable registration algorithms and automatic segmentation for:
* dose adaptation on the basis of a displacement field obtained by image co-registration, which could nevetheless lead to non consistent plans both from physics and technology point of view (i.e. are not deliverable).
* organ shape prediction both intra- and across patients
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<h3>Approach, Plan</h3>

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<h3>Progress</h3>

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==Delivery Mechanism==

==References==

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 <h3>Progress</h3>
-will be filled by the end of the week
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 <h3>Approach, Plan</h3>
 One crucial step of this approach is the rigid alignment prior to deformable registration. For CT/CBCT co-registration, this is even more difficult given the presence of immobilization devices (e.g. thermoplastic masks) and the different image quality.
 We tested out both Versor and Quaternions (currently in slicer) and the plan for the week is to gain a better understanding of both in terms of:
-- stopping conditions (i.e. no stopping condition for quaternions?)
+* stopping conditions (i.e. no stopping condition for quaternions?)
-- computational velocity
+* computational velocity
-- improvement to reduct influence of metal artifacts and different image quality on the final output
+* improvement to reduct influence of metal artifacts and different image quality on the final output
 The plan includes the implementation of possible solution that address this problem.
 A side problem includes the removal of the immobilization devices + tube artifacts from CBCT images. At the moment we proceed with a combination of registration and erode/dilate morphological operations given a contour on a previous image, but we would be happy to discuss about this :) (NB: maybe smt similar to the skull stripping algorithm would help us?)

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 <gallery>
 Image:PW-MIT2010.png|[[2010_Summer_Project_Week#Projects|Projects List]]
-Image:HNCBCT.jpg|Sample Image Dataset.
+File:HN_CBCT.png|Sample Image Dataset.
 Image:RegistrationRigidHN.png|Sample Image Registration Output.
 </gallery>

@@ Line 2: / Line 2: @@
 <gallery>
 Image:PW-MIT2010.png|[[2010_Summer_Project_Week#Projects|Projects List]]
-Image:[[File:HN_CBCT.jpg]]|Sample Image Dataset.
+Image:HNCBCT.jpg|Sample Image Dataset.
-Image:HN_rigid.jpg|Sample Image Registration Output.
+Image:RegistrationRigidHN.png|Sample Image Registration Output.
 </gallery>

@@ Line 2: / Line 2: @@
 <gallery>
 Image:PW-MIT2010.png|[[2010_Summer_Project_Week#Projects|Projects List]]
-Image:HN_CBCT.jpg|Sample Image Dataset.
+Image:[[File:HN_CBCT.jpg]]|Sample Image Dataset.
 Image:HN_rigid.jpg|Sample Image Registration Output.
 </gallery>