2010 Summer Project Week Shape - Revision history

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Tammy: Created page with 'NOTOC Image:PW-MIT2010.png|Projects List ==Key Investigators== * MIT: Tammy Riklin Raviv * BWH: Sylvain Bouix ==…'

2010-06-04T14:37:35Z

Created page with '__NOTOC__ <gallery> Image:PW-MIT2010.png|Projects List </gallery> ==Key Investigators== * MIT: Tammy Riklin Raviv * BWH: Sylvain Bouix ==…'

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__NOTOC__
<gallery>
Image:PW-MIT2010.png|[[2010_Summer_Project_Week#Projects|Projects List]]
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==Key Investigators==
* MIT: Tammy Riklin Raviv
* BWH: Sylvain Bouix

==Project==
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<h3>Objective</h3>
Group-wise statistical analysis of brain structures is significant for clinical and neuroanatomy studies. Nevertheless, due the inherent difficulty to properly represent the morphology of the structures of interest, the statistics is usually limited to volume and surface area measurements. Ideally, we would require an injective shape representation that is invariant rigid or even affine transformations and form a vector space. In the absence of shape representation that meets all of these requirements, it is difficult to define fundamental concepts such as the median or average shape.
We defined a novel measure for shape dissimilarity that is based on shape boundaries. This measure allows us to construct the 'median' of shapes of the same class that provides reacher morphological characteristics of the ensemble. Our goal in this project is to apply the proposed method to a population study of brain structures and test its discriminative power.
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<h3>Approach, Plan</h3>
We use a variational framework based on level-sets to deform a representative (canonical) shape such that the sum of its distances from each of the shapes in the group is minimized.
We will first test the approach on a set of synthetic shapes where the resulting median shape can be validated. The outcomes of this preliminary stage are expected to guide us in planning more advanced experiments.
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<h3>Progress</h3>

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@@ Line 12: / Line 12: @@
 <div style="width: 30%; float: left; padding-right: 2%;">
 <h3>Objective</h3>
-Group-wise statistical analysis of brain structures is significant for clinical and neuroanatomy studies. Nevertheless, due to the inherent difficulty to properly represent the morphology of the structures of interest, the statistics is usually limited to volume and surface area measurements. Ideally, we would require an injective shape representation that is invariant rigid or even affine transformations and form a vector space. In the absence of shape representation that meets all of these requirements, it is difficult to define fundamental concepts such as the median or average shape.
+Defining the canonical/median shape having group of shapes.
 </div>
 <div style="width: 30%; float: left; padding-right: 2%;">
 <h3>Approach, Plan</h3>
 We will first test the approach on a set of synthetic shapes where the resulting median shape can be validated. The outcomes of this preliminary stage are expected to guide us in planning more advanced experiments.
 </div>
@@ Line 26: / Line 23: @@
 <h3>Progress</h3>
 We made progress in the process of transforming the Matlab code into ITK.
-Specifically we worked on building a new ITK boundary-based shape metric and incorporating it into our registration framework prior to the construction
+Specifically we worked on building a new ITK shape metric and incorporating it into our registration framework prior to the construction
-of the boundary-based median shape.
+of the 'median' shape.
 </div>

@@ Line 26: / Line 26: @@
 <h3>Progress</h3>
 We made progress in the process of transforming the Matlab code into ITK.
-Specifically we worked on building a new ITK boundary based metric and incorporating it into our registration framework prior to the construction
+Specifically we worked on building a new ITK boundary-based shape metric and incorporating it into our registration framework prior to the construction
 of the boundary-based median shape.
 </div>

@@ Line 25: / Line 25: @@
 <div style="width: 35%; float: left;">
 <h3>Progress</h3>
-We are about half way in the process of transforming the Matlab code into ITK.
+We made progress in the process of transforming the Matlab code into ITK.
 Specifically we worked on building a new ITK boundary based metric and incorporating it into our registration framework prior to the construction
 of the boundary-based median shape.
 </div>

@@ Line 25: / Line 25: @@
 <div style="width: 35%; float: left;">
 <h3>Progress</h3>
-We are about half way in the process of transforming the Matlab code into ITK having successful preliminary results.
+We are about half way in the process of transforming the Matlab code into ITK.
 </div>

2010 Summer Project Week Shape - Revision history

Tammy: /* Project */

Tammy: /* Project */

Tammy: /* Project */

Tammy: /* Project */

Tammy: /* Project */

Tammy: /* Project */

Tammy: /* Project */

Tammy: Created page with '__NOTOC__ Image:PW-MIT2010.png|Projects List ==Key Investigators== * MIT: Tammy Riklin Raviv * BWH: Sylvain Bouix ==…'

Tammy: Created page with 'NOTOC Image:PW-MIT2010.png|Projects List ==Key Investigators== * MIT: Tammy Riklin Raviv * BWH: Sylvain Bouix ==…'