2013 Project Week:Imaging Genetic for Stroke - Revision history

Adalca at 23:10, 10 January 2013

2013-01-10T23:10:05Z

Adalca: /* Project Description */

2013-01-03T19:04:33Z

Project Description

Adalca at 19:03, 3 January 2013

2013-01-03T19:03:58Z

Adalca: moved 2013 Winter Project Week:Imaging Genetic for Stroke to 2013 Project Week:Imaging Genetic for Stroke

2013-01-03T18:56:59Z

moved 2013 Winter Project Week:Imaging Genetic for Stroke to 2013 Project Week:Imaging Genetic for Stroke

Adalca: Created page with 'NOTOC Image:PW-SLC2013.png|Projects List Image:WMH_T1.png‎| T1 images in stroke dataset. Image:WMHseg.png | left: FLAIR ima…'

2013-01-03T18:56:21Z

Created page with '__NOTOC__ <gallery> Image:PW-SLC2013.png|Projects List Image:WMH_T1.png‎| T1 images in stroke dataset. Image:WMHseg.png | left: FLAIR ima…'

New page

__NOTOC__

<gallery>
Image:PW-SLC2013.png|[[2013_Winter_Project_Week#Projects|Projects List]]
Image:WMH_T1.png‎| T1 images in stroke dataset.
Image:WMHseg.png | left: FLAIR images, middle: manual delineation of 'interesting' areas, right: manual WMH segmentation.
</gallery>

==Key Investigators==

* Adrian Dalca, Kayhan Batmanghelich, Polina Golland, MIT
* Natalia Rost, Jonathan Rosand, MGH

==Project Description==

<div style="margin: 20px;">
<div style="width: 27%; float: left; padding-right: 3%;">
<h3>Objective</h3>
We want to expand and explore a imaging genetics model developed in our lab for (potentially continuous) phenotypes in stroke patients. Combined with the [[2013 Winter Project Week:WMH Segmentation|WMH Segmentation]]

We are developing methods for segmentation of white matter hyperintensity in FLAIR images of stroke patients. Specifically, WMH is to be localized in particular areas of the brain, as seen in a training set. This dataset is particularly challenging due to the low resolution (1mm x 1mm x 7mm) and with cropped fields of view in the given images.
</div>
<div style="width: 27%; float: left; padding-right: 3%;">
<h3>Approach, Plan</h3>
* Find and apply appropriate registration method to register cropped, low resolution T1 scans
* Register T1 scans to FLAIR images with rigid registration
* Create mask of relevant areas for WMH segmentation from manual segmentations
* Investigate several known methods for segmentation of WMH segmentation using training images.
* Write thorough pipline for above steps.
</div>
<div style="width: 27%; float: left; padding-right: 3%;">
<h3>Progress</h3>
*
</div>
</div>

@@ Line 15: / Line 15: @@
 <div style="width: 27%; float: left; padding-right: 3%;">
 <h3>Objective</h3>
-We want to explore a imaging genetics model and identify (potentially continuous) phenotypes in stroke patients. Combined with the [[2013_Project_Week:WMH_Segmentation_for_Stroke|WMH segmentation]], we will start with WMH-based imaging phenotypes.
+We want to explore an imaging genetics model and identify (potentially continuous) phenotypes in stroke patients. Combined with the [[2013_Project_Week:WMH_Segmentation_for_Stroke|WMH segmentation]], we will start with WMH-based imaging phenotypes.
 </div>
 <div style="width: 27%; float: left; padding-right: 3%;">
@@ Line 22: / Line 22: @@
 * Construct distribution map of WMH
 * Explore clustering of WMH
-* Explore current imaging genetics model developed in our lab with above phenotypes and stroke dataset genotypes.
+* Expand/Explore current imaging genetics model developed in our lab with above phenotypes and stroke dataset genotypes.
 </div>
 <div style="width: 27%; float: left; padding-right: 3%;">

@@ Line 26: / Line 26: @@
 <div style="width: 27%; float: left; padding-right: 3%;">
 <h3>Progress</h3>
+* Almost completed the [[2013_Project_Week:WMH_Segmentation_for_Stroke|WMH pipeline]].
 </div>
 </div>

@@ Line 3: / Line 3: @@
 <gallery>
 Image:PW-SLC2013.png|[[2013_Winter_Project_Week#Projects|Projects List]]
 </gallery>
@@ Line 17: / Line 15: @@
 <div style="width: 27%; float: left; padding-right: 3%;">
 <h3>Objective</h3>
-We want to expand and explore a imaging genetics model developed in our lab for (potentially continuous) phenotypes in stroke patients. Combined with the [[2013 Winter Project Week:WMH Segmentation|WMH Segmentation]]
+We want to explore a imaging genetics model and identify (potentially continuous) phenotypes in stroke patients. Combined with the [[2013_Project_Week:WMH_Segmentation_for_Stroke|WMH segmentation]], we will start with WMH-based imaging phenotypes.
 </div>
 <div style="width: 27%; float: left; padding-right: 3%;">
 <h3>Approach, Plan</h3>
-* Find and apply appropriate registration method to register cropped, low resolution T1 scans
+* Run through the WMH pipeline.
-* Register T1 scans to FLAIR images with rigid registration
+* Construct distribution map of WMH
-* Create mask of relevant areas for WMH segmentation from manual segmentations
+* Explore clustering of WMH
-* Investigate several known methods for segmentation of WMH segmentation using training images.
+* Explore current imaging genetics model developed in our lab with above phenotypes and stroke dataset genotypes.
 </div>
 <div style="width: 27%; float: left; padding-right: 3%;">