CTSC:CHBresources:nuclear medicine - Revision history

Valerie.humblet at 19:54, 1 March 2011

2011-03-01T19:54:01Z

Valerie.humblet: /* =Division of Nuclear Medicine at Waltham */

2009-07-10T03:43:02Z

=Division of Nuclear Medicine at Waltham

Valerie.humblet: /* PET */

2009-07-10T03:42:48Z

PET

Valerie.humblet: /* Radiopharmaceutical Chemistry Laboratory */

2009-07-08T19:34:51Z

Radiopharmaceutical Chemistry Laboratory

Valerie.humblet at 19:31, 8 July 2009

2009-07-08T19:31:37Z

Valerie.humblet at 19:20, 8 July 2009

2009-07-08T19:20:32Z

Valerie.humblet: /* Imaging equipment */

2009-07-08T19:19:07Z

Imaging equipment

Valerie.humblet at 19:15, 8 July 2009

2009-07-08T19:15:37Z

Valerie.humblet at 19:13, 8 July 2009

2009-07-08T19:13:12Z

Valerie.humblet: /* SPECT */

2009-07-08T19:12:47Z

SPECT

@@ Line 1: / Line 1: @@
 [[CTSC:CHBresources|Back to CHB Imaging Resources]]
-The Division of Nuclear Medicine at Children’s Hospital Boston has a full service radiopharmacy, 4 routine imaging rooms, a PET Suite, one portable imaging camera, and a stationary planar imaging system in the Division of Urodynamics.
+The Division of Nuclear Medicine and Molecular Imaging at Children’s Hospital Boston includes two clinical units, a radiopharmaceutical research unit, and a small animal imaging research lab.
 =SPECT=
@@ Line 9: / Line 15: @@
 ==Imaging Equipment==
-* 2 Siemens Single Head E.CAM Imaging Systems
+* 4 Siemens SPECT-capable gamma camera I
 * 1 DigiRAD Single Head Portable Imaging System
 == Processing Workstations==

@@ Line 36: / Line 36: @@
 * Hermes Windows Client: used to facilitate image fusion of PET imaging studies to cross-sectional imaging performed by either CT or MRI, to allow correlation of functional and anatomic data  in addition to conventional planar imaging.
-==Division of Nuclear Medicine at Waltham=
+==Division of Nuclear Medicine at Waltham==
 * 1 Siemens Dual Head E.Cam SPECT Imaging System with a Siemens E.Soft A/P Workstation

← Older revision		Revision as of 03:42, 10 July 2009
Line 35:		Line 35:

	* Hermes Windows Client: used to facilitate image fusion of PET imaging studies to cross-sectional imaging performed by either CT or MRI, to allow correlation of functional and anatomic data in addition to conventional planar imaging.		* Hermes Windows Client: used to facilitate image fusion of PET imaging studies to cross-sectional imaging performed by either CT or MRI, to allow correlation of functional and anatomic data in addition to conventional planar imaging.
		+
		+	==Division of Nuclear Medicine at Waltham=
		+
		+	* 1 Siemens Dual Head E.Cam SPECT Imaging System with a Siemens E.Soft A/P Workstation
		+
		+	* Processing Workstations:<br>
		+	- Hermes Client Workstation <br>
		+	- Esoft Workstation (ipwal1) Processing

	=Radiopharmaceutical Chemistry Laboratory=		=Radiopharmaceutical Chemistry Laboratory=

@@ Line 38: / Line 38: @@
 =Radiopharmaceutical Chemistry Laboratory=
-The radiopharmaceutical chemistry laboratory contains four fume hoods, approximately 50 linear feet of bench space, and is set up to accommodate three postdoctoral researchers. The laboratory is equipped with various chemical instrumentation including a Bruker FTIR spectrometer, a Perkin-Elmer Lambda 40 uv-visible spectrophotometer, and a Hitachi high-performance liquid chromatograph equipped with a diode array and a gamma detector. Other smaller pieces of equipment (centrifuges, pH meters, etc.) are also available.
+The radiopharmaceutical chemistry research program occupies two research laboratories in the Enders research building at Children's: a radiopharmaceutical chemistry laboratory and a "hot" laboratory. A separate cell-culture laboratory is also available.
-The hot laboratory is used for handling high levels of radioactivity and has a shielded fume hood that is equipped with a pair of Tru-Motion remote manipulator arms. This laboratory is also equipped with a semi-preparative HPLC system for purification of 18F-labeled compounds. This laboratory is scheduled for renovation in the spring of 2008. The renovation will include the addition of a hot cell suitable for the preparation of higher levels of 18F-labeled compounds than can be accommodated in the existing facility. In addition to our own basic science investigations, this laboratory is also used for the preparation of 18F-labeled compounds for use by CHB microPET users.
+==Radiopharmaceutical chemistry laboratory==

← Older revision		Revision as of 19:31, 8 July 2009
Line 35:		Line 35:

	* Hermes Windows Client: used to facilitate image fusion of PET imaging studies to cross-sectional imaging performed by either CT or MRI, to allow correlation of functional and anatomic data in addition to conventional planar imaging.		* Hermes Windows Client: used to facilitate image fusion of PET imaging studies to cross-sectional imaging performed by either CT or MRI, to allow correlation of functional and anatomic data in addition to conventional planar imaging.
		+
		+	=Radiopharmaceutical Chemistry Laboratory=
		+
		+	The radiopharmaceutical chemistry laboratory contains four fume hoods, approximately 50 linear feet of bench space, and is set up to accommodate three postdoctoral researchers. The laboratory is equipped with various chemical instrumentation including a Bruker FTIR spectrometer, a Perkin-Elmer Lambda 40 uv-visible spectrophotometer, and a Hitachi high-performance liquid chromatograph equipped with a diode array and a gamma detector. Other smaller pieces of equipment (centrifuges, pH meters, etc.) are also available.
		+
		+	The hot laboratory is used for handling high levels of radioactivity and has a shielded fume hood that is equipped with a pair of Tru-Motion remote manipulator arms. This laboratory is also equipped with a semi-preparative HPLC system for purification of 18F-labeled compounds. This laboratory is scheduled for renovation in the spring of 2008. The renovation will include the addition of a hot cell suitable for the preparation of higher levels of 18F-labeled compounds than can be accommodated in the existing facility. In addition to our own basic science investigations, this laboratory is also used for the preparation of 18F-labeled compounds for use by CHB microPET users.

@@ Line 21: / Line 21: @@
 * GE Xeleris
 * GE Advantage
 =PET=

@@ Line 29: / Line 29: @@
 ==Imaging equipment==
-* 1 GE Advance NXi PET scanner dedicated for pediatric use, providing resolution of structures 8-10 mm in size. Imaging is routinely performed with 18F and 18F-FDG; other positron-emitting radionuclides such as 11C and 64Cu can be imaged as they become available.
+* 1 GE Advance NXi PET scanner dedicated for pediatric use, providing resolution of structures 8-10 mm in size. Imaging is routinely performed with 18F and 18F-FDG; other positron-emitting radionuclides such as 11C and 64Cu can be imaged as they become available. It consists of 12,096 small (4x8mm) bismuth germanate (BGO) scintillating detectors that can simultaneously image 35 tomographic slices over a 15.4 cm axial field of view. The spatial resolution of the Advance NXi is 4.9 mm. The sensitivity of the scanner is 200 and 1000 thousand counts per second per mCi per mL for 2D and 3D PET mode, respectively. Activity concentrations up to 220 kBq/mL (6 μCi/mL) can be suitably measured. Measured attenuation correction necessary for accurate quantitation is provided with the use of two rotating sources of 68Ge/68Ga.
 * The PET data is reconstructed using the ordered subset expectation maximization (OSEM) iterative algorithm in a manner suitable for further advanced image processing including kinetic modeling, display using standard uptake values (SUV) and image registration with either MR or CT images. The PET image data can also be made readily available to other analysis workstations using either the interfile or DICOM image format. Post-processing capabilities include standard multiplanar reconstruction techniques, as well as two Hermes workstations.

@@ Line 3: / Line 3: @@
 The Division of Nuclear Medicine at Children’s Hospital Boston has a full service radiopharmacy, 4 routine imaging rooms, a PET Suite, one portable imaging camera, and a stationary planar imaging system in the Division of Urodynamics.
-===SPECT===
+=SPECT=
 SPECT cameras available for imaging with traditional gamma-emitting agents such as 123I and 99mTc.