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		<title>Andy: Update from Wiki</title>
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		<updated>2006-12-18T19:35:01Z</updated>

		<summary type="html">&lt;p&gt;Update from Wiki&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;== Testing Methods for Statistical Shape Analysis ==&lt;br /&gt;
&lt;br /&gt;
=== Description ===&lt;br /&gt;
&lt;br /&gt;
3 Main correction methods in local statistical shape analysis for the multiple comparison problem exists.&lt;br /&gt;
&lt;br /&gt;
# Bonferroni correction (simple, worst case, conservative)&lt;br /&gt;
# Minimum statistic using Non-parametric permutation tests (less conservative than Bonferroni, full control of family wise error rate (FWER, Type I error, false positives), still pessimistic)&lt;br /&gt;
# False Discovery Rate (FDR, control of false discovery rate, i.e. control of false positive in only those features that reject Null Hypothesis, less conservative)&lt;br /&gt;
&lt;br /&gt;
Currently the UNC shape analysis pipeline incorporates the permutation test based correction technique. This project will&lt;br /&gt;
&lt;br /&gt;
* extend the shape analysis pipeline to incorporate Bonferroni and FDR&lt;br /&gt;
* change the current code to use the ITK statistics framework&lt;br /&gt;
&lt;br /&gt;
=== Current Status ===&lt;br /&gt;
&lt;br /&gt;
* permutation tests are working&lt;br /&gt;
* both bonferroni and FDR will be rather simple to implement, the bulk of work will be associated with transfering the code into the ITK framework&lt;br /&gt;
* [[Image:2006_06_PW_StatAnal.ppt|Image:2006 06 PW StatAnal.ppt]]&lt;br /&gt;
&lt;br /&gt;
=== Members ===&lt;br /&gt;
&lt;br /&gt;
* Martin Styner (UNC)&lt;/div&gt;</summary>
		<author><name>Andy</name></author>
		
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