NA-MIC Childrens Collaboration - Revision history

Marianna: /* Publications */

2016-12-14T17:18:58Z

Publications

Marianna: /* Publications */

2010-05-14T14:43:32Z

Publications

Marianna: /* Introduction */

2010-05-14T14:38:10Z

Introduction

Marianna at 19:14, 16 December 2009

2009-12-16T19:14:06Z

Marianna: /* Building and Running SCIRun on SPL Machines */

2009-12-02T15:18:03Z

Building and Running SCIRun on SPL Machines

Mjolley at 04:22, 11 December 2008

2008-12-11T04:22:12Z

Marianna: /* Citations */

2008-05-08T20:11:33Z

Citations

Marianna: /* Citations */

2008-02-14T22:03:19Z

Citations

Mjolley: /* Citations */

2008-01-23T09:21:11Z

Citations

Mjolley: /* Building and Running SCIRun on SPL Machines */

2008-01-23T09:20:06Z

Building and Running SCIRun on SPL Machines

@@ Line 38: / Line 38: @@
 *Jolley M, Stinstra J, Weinstein D, et al. Open-Source Environment for Interactive Finite Element Modeling of Optimal ICD Electrode Placement Functional Imaging and Modeling of the Heart, Lecture Notes in Computer Science. Berlin/Heidelberg: Springer, 2007:373-382.
 *Jolley M, Stinstra J, Weinsten D, et al. Finite Element Modeling of Novel Defibrillation Approaches in Children and Adult Heart Rhythm Society. Denver, Colorado, 2007.
-*Jolley M, Triedman J, Westin C, Weinstein D, MacLeod R, Brooks D. [http://www.na-mic.org/publications/item/view/1240 Image based modeling of defibrillation in children.] Conf Proc IEEE Eng Med Biol Soc. 2006;1:2564-7.
+*Jolley M., Triedman J., Westin C-F., Weinstein D.M., MacLeod R., Brooks D.H.  [http://www.na-mic.org/publications/item/view/1240 Image Based Modeling of Defibrillation in Children.] Conf Proc IEEE Eng Med Biol Soc. 2006 Sep;1:2564-7. PMID: 17946966.
-* Stinstra J, Jolley M, Callahan M, Weinstein D, Cole M, Brooks D, Triedman J, Macleod R. [http://www.na-mic.org/publications/item/view/1241 Evaluation of different meshing algorithms in the computation of defibrillation thresholds in children.] Conf Proc IEEE Eng Med Biol Soc. 2007;2007:1422-5.
+* Stinstra J.G., Jolley M., Callahan M., Weinstein D., Cole M., Brooks D.H., Triedman J.K., Macleod R.S.  [http://www.na-mic.org/publications/item/view/1241 Evaluation of Different Meshing Algorithms in the Computation of Defibrillation Thresholds in Children.] Conf Proc IEEE Eng Med Biol Soc. 2007 Aug;2007:1422-5. PMID: 18002232.
-*Jolley M, Stinstra J, Pieper S, Macleod R, Brooks D, Cecchin F, Triedman J. [http://www.na-mic.org/publications/item/view/1277 A Computer Modeling Tool for Comparing Novel ICD Electrode Orientations in Children and Adults.] Heart Rhythm. 2008 Apr;5(4):565-572.
+*Jolley M., Stinstra J.G., Pieper S., Macleod R.S., Brooks D.H., Cecchin F., Triedman J.K.  [http://www.na-mic.org/publications/item/view/1277 A Computer Modeling Tool for Comparing Novel ICD Electrode Orientations in Children and Adults.] Heart Rhythm. 2008 Apr;5(4):565-72. PMID: 18362024. PMCID: PMC2745086.

@@ Line 38: / Line 38: @@
 *Jolley M, Stinstra J, Weinstein D, et al. Open-Source Environment for Interactive Finite Element Modeling of Optimal ICD Electrode Placement Functional Imaging and Modeling of the Heart, Lecture Notes in Computer Science. Berlin/Heidelberg: Springer, 2007:373-382.
 *Jolley M, Stinstra J, Weinsten D, et al. Finite Element Modeling of Novel Defibrillation Approaches in Children and Adult Heart Rhythm Society. Denver, Colorado, 2007.
-*Jolley M, Triedman J, Westin C, Weinstein D, MacLeod R, Brooks D. [http://www.na-mic.org/publications/item/view/1240 Image based modeling of defibrillation in children.] Conf Proc IEEE Eng Med Biol Soc. 2006;1:2564-7. PMID: 17946966.
+*Jolley M, Triedman J, Westin C, Weinstein D, MacLeod R, Brooks D. [http://www.na-mic.org/publications/item/view/1240 Image based modeling of defibrillation in children.] Conf Proc IEEE Eng Med Biol Soc. 2006;1:2564-7.
-* Stinstra J, Jolley M, Callahan M, Weinstein D, Cole M, Brooks D, Triedman J, Macleod R. [http://www.na-mic.org/publications/item/view/1241 Evaluation of different meshing algorithms in the computation of defibrillation thresholds in children.] Conf Proc IEEE Eng Med Biol Soc. 2007;2007:1422-5. PMID: 18002232.
+* Stinstra J, Jolley M, Callahan M, Weinstein D, Cole M, Brooks D, Triedman J, Macleod R. [http://www.na-mic.org/publications/item/view/1241 Evaluation of different meshing algorithms in the computation of defibrillation thresholds in children.] Conf Proc IEEE Eng Med Biol Soc. 2007;2007:1422-5.
-*Jolley M, Stinstra J, Pieper S, Macleod R, Brooks D, Cecchin F, Triedman J. [http://www.na-mic.org/publications/item/view/1277 A Computer Modeling Tool for Comparing Novel ICD Electrode Orientations in Children and Adults.] Heart Rhythm. 2008 Apr;5(4):565-572. PMID: 18362024. PMCID: PMC2745086.
+*Jolley M, Stinstra J, Pieper S, Macleod R, Brooks D, Cecchin F, Triedman J. [http://www.na-mic.org/publications/item/view/1277 A Computer Modeling Tool for Comparing Novel ICD Electrode Orientations in Children and Adults.] Heart Rhythm. 2008 Apr;5(4):565-572.

@@ Line 10: / Line 10: @@
 ==Introduction==
-Placement of  Implantable Cardiac Defibrillators(ICDs)is a unique and challenging problem for children due to the variety of shapes and sizes, ranging from neonate to adolescent.  As a result, a variety of novel implant techniques have been employed.  Although these have generally been successful inasmuch as they result in a clinically acceptable defibrillation threshold, nothing is known about the mechanisms by which this threshold is attained, the optimal geometries for defibrillation, and whether unsafe electric field strengths are a result of novel implant approaches.  Finite element modeling has been shown in adult torso models to correlate well with clinical results.  Our goal is to model defibrillation in child torso models to gain insight into this important problem.  We are also interested in developing new orientations in adults with the goal of lowering DFTs and providing options in patients with contraindications to standard techniques.
+Placement of  Implantable Cardiac Defibrillators(ICDs) is a unique and challenging problem for children due to the variety of shapes and sizes, ranging from neonate to adolescent.  As a result, a variety of novel implant techniques have been employed.  Although these have generally been successful inasmuch as they result in a clinically acceptable defibrillation threshold, nothing is known about the mechanisms by which this threshold is attained, the optimal geometries for defibrillation, and whether unsafe electric field strengths are a result of novel implant approaches.  Finite element modeling has been shown in adult torso models to correlate well with clinical results.  Our goal is to model defibrillation in child torso models to gain insight into this important problem.  We are also interested in developing new orientations in adults with the goal of lowering DFTs and providing options in patients with contraindications to standard techniques.
 ==Key Personnel==

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-Back to [[NA-MIC_External_Collaborations]]
+__NOTOC__
 {|
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 |}
-= Introduction =
+==Introduction==
 Placement of  Implantable Cardiac Defibrillators(ICDs)is a unique and challenging problem for children due to the variety of shapes and sizes, ranging from neonate to adolescent.  As a result, a variety of novel implant techniques have been employed.  Although these have generally been successful inasmuch as they result in a clinically acceptable defibrillation threshold, nothing is known about the mechanisms by which this threshold is attained, the optimal geometries for defibrillation, and whether unsafe electric field strengths are a result of novel implant approaches.  Finite element modeling has been shown in adult torso models to correlate well with clinical results.  Our goal is to model defibrillation in child torso models to gain insight into this important problem.  We are also interested in developing new orientations in adults with the goal of lowering DFTs and providing options in patients with contraindications to standard techniques.
-= Participants =
+==Key Personnel==
-===Stanford===
+*Stanford: Matthew Jolley, Anne Dubin, Paul Wang
-Matthew Jolley, Anne Dubin, Paul Wang
+*Children's Hospital Boston: John Triedman, Frank Cecchin
-===Children's Hospital Boston===
+*Scientific Computing Institute, Utah: Jeroen Stinstra, Rob Macleod
-John Triedman, Frank Cecchin
+*NorthEastern University: Dana Brooks
-===Scientific Computing Institute, Utah===
+*NA-MIC: Steve Pieper, Kilian Pohl
 = Goals of Project =

@@ Line 39: / Line 39: @@
 [[SCRun on SPL Machines]]
-=== Citations ===
+==Publications==
+*Jolley M, Stinstra J, Weinstein D, et al. Open-Source Environment for Interactive Finite Element Modeling of Optimal ICD Electrode Placement Functional Imaging and Modeling of the Heart, Lecture Notes in Computer Science. Berlin/Heidelberg: Springer, 2007:373-382.
-. Jolley M, Stinstra J, Weinstein D, et al. Open-Source Environment for Interactive Finite Element Modeling of Optimal ICD Electrode Placement Functional Imaging and Modeling of the Heart, Lecture Notes in Computer Science. Berlin/Heidelberg: Springer, 2007:373-382.
+*Jolley M, Stinstra J, Weinsten D, et al. Finite Element Modeling of Novel Defibrillation Approaches in Children and Adult Heart Rhythm Society. Denver, Colorado, 2007.
+*Jolley M, Triedman J, Westin C, Weinstein D, MacLeod R, Brooks D. [http://www.na-mic.org/publications/item/view/1240 Image based modeling of defibrillation in children.] Conf Proc IEEE Eng Med Biol Soc. 2006;1:2564-7. PMID: 17946966.
-. Jolley M, Stinstra J, Weinsten D, et al. Finite Element Modeling of Novel Defibrillation Approaches in Children and Adult Heart Rhythm Society. Denver, Colorado, 2007.
+* Stinstra J, Jolley M, Callahan M, Weinstein D, Cole M, Brooks D, Triedman J, Macleod R. [http://www.na-mic.org/publications/item/view/1241 Evaluation of different meshing algorithms in the computation of defibrillation thresholds in children.] Conf Proc IEEE Eng Med Biol Soc. 2007;2007:1422-5. PMID: 18002232.
+*Jolley M, Stinstra J, Pieper S, Macleod R, Brooks D, Cecchin F, Triedman J. [http://www.na-mic.org/publications/item/view/1277 A Computer Modeling Tool for Comparing Novel ICD Electrode Orientations in Children and Adults.] Heart Rhythm. 2008 Apr;5(4):565-572. PMID: 18362024. PMCID: PMC2745086.

@@ Line 7: / Line 7: @@
 |}
-=== Introduction ===
+= Introduction =
 Placement of  Implantable Cardiac Defibrillators(ICDs)is a unique and challenging problem for children due to the variety of shapes and sizes, ranging from neonate to adolescent.  As a result, a variety of novel implant techniques have been employed.  Although these have generally been successful inasmuch as they result in a clinically acceptable defibrillation threshold, nothing is known about the mechanisms by which this threshold is attained, the optimal geometries for defibrillation, and whether unsafe electric field strengths are a result of novel implant approaches.  Finite element modeling has been shown in adult torso models to correlate well with clinical results.  Our goal is to model defibrillation in child torso models to gain insight into this important problem.  We are also interested in developing new orientations in adults with the goal of lowering DFTs and providing options in patients with contraindications to standard techniques.
-=== Goals of Project ===
+= Participants =
-.  Create 3D models of children based on CT and MRI datasets for modeling internal and external defibrillation in the SCIRun environment.  The processes required address the larger question of how to take any CT or MRI DICOM dataset, segment it into various label maps, combine those label maps in a hierarchical manner, then import and utilize them in the SCIRun/BioPSE environment.  This represents part of an expanding collaboration between [http://www.sci.utah.edu/ SCI] and [http://splweb.bwh.harvard.edu:8000/ SPL] to integrate open source tools to allow creation, visualization, and computational modeling of image based 3D models.
+= Goals of Project =
-.  Create modules which allow insertion of electrode shapes into finite element models in in the SCIRun environment.
+==Segmentation==
-.  Utilize the above innovations to model the placement of internal defibrillator electrodes to maximize efficacy, minimize potential cardiac damage, and gain further insight into optimizing defibrillation in children of various sizes as shown above.
+Segmentation is currently done using tools within the open source tools 3D Slicer and Seg3D.  We are actively working with members of SCI and SPL on developing automated segmentation techniques for torso and cardiac modeling.  In the future we would like to integrate DT-MRI fiber structure into our cardiac models.
-=== Slicer and SPL Tools in the Project ===
+==Modeling==
-[[Outline of Torso Segmentation Problem]]
+We have worked with members of the SCI Institute in Utah to develop a modeling framework within their SCIRun package which allows rapid placement of realistic electrodes within finite element models of adult and child torsos.  All tools to do so are available open source to download from the SCI website.  We continue to improve this platform, integrating new technology and insight as we progress.
-[[Segmentation Tools Currently Utilized]]
+= Building and Running SCIRun on SPL Machines =
 [[SCRun on SPL Machines]]

← Older revision		Revision as of 20:11, 8 May 2008
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	4. Stinstra JG, Jolley M, Callahan M, et al. Evaluation of different meshing algorithms in the computation of defibrillator thresholds in children. Conf Proc IEEE Eng Med Biol Soc 2007;1:1422-5.		4. Stinstra JG, Jolley M, Callahan M, et al. Evaluation of different meshing algorithms in the computation of defibrillator thresholds in children. Conf Proc IEEE Eng Med Biol Soc 2007;1:1422-5.

−	5. Matthew Jolley, Jeroen Stinstra, Steve Pieper, Rob MacLeod, Dana H. Brooks, Frank Cecchin, John K. Triedman A Computer Modeling Tool for Comparing Novel ICD Electrode Orientations in Children and Adults. ~~In Press Accepted Manuscript for~~ Heart Rhythm~~, Available online 18 January~~ 2008~~, http~~:~~//www.heartrhythmjournal~~.~~com/inpress~~	+	5. Matthew Jolley, Jeroen Stinstra, Steve Pieper, Rob MacLeod, Dana H. Brooks, Frank Cecchin, John K. Triedman A Computer Modeling Tool for Comparing Novel ICD Electrode Orientations in Children and Adults. Heart Rhythm. 2008 Apr;5(4):565-572.

@@ Line 38: / Line 38: @@
 . Jolley M, Triedman J, Westin CF, et al. Image based modeling of defibrillation in children. Conf Proc IEEE Eng Med Biol Soc 2006;1:2564-7.
-. Stinstra JG, Jolley M, Callahan M, et al. Evaluation of different meshing algorithms in the computation of defibrillation thresholds in children. Conf Proc IEEE Eng Med Biol Soc 2007;1:1422-5.
+. Stinstra JG, Jolley M, Callahan M, et al. Evaluation of different meshing algorithms in the computation of defibrillator thresholds in children. Conf Proc IEEE Eng Med Biol Soc 2007;1:1422-5.
-.  A Computer Modeling Tool for Comparing Novel ICD Electrode Orientations in Children and Adults. In Press Accepted Manuscript for Heart Rhythm, Available online 18 January 2008, http://www.heartrhythmjournal.com/inpress
+. Matthew Jolley, Jeroen Stinstra, Steve Pieper, Rob MacLeod, Dana H. Brooks, Frank Cecchin, John K. Triedman  A Computer Modeling Tool for Comparing Novel ICD Electrode Orientations in Children and Adults. In Press Accepted Manuscript for Heart Rhythm, Available online 18 January 2008, http://www.heartrhythmjournal.com/inpress