https://www.na-mic.org/w/index.php?action=history&feed=atom&title=Projects%3AAtlasBasedSusceptibilityMappingProjects:AtlasBasedSusceptibilityMapping - Revision history2026-04-07T06:08:19ZRevision history for this page on the wikiMediaWiki 1.33.0https://www.na-mic.org/w/index.php?title=Projects:AtlasBasedSusceptibilityMapping&diff=65472&oldid=prevCpoynton: Created page with 'Quantifying magnetic susceptibility in the brain from the phase of the MR signal provides a non-invasive means for measuring the accumulation of iron believed to occur with aging…'2011-03-23T20:02:12Z<p>Created page with 'Quantifying magnetic susceptibility in the brain from the phase of the MR signal provides a non-invasive means for measuring the accumulation of iron believed to occur with aging…'</p>
<p><b>New page</b></p><div>Quantifying magnetic susceptibility in the brain from the phase of the MR signal<br />
provides a non-invasive means for measuring the accumulation<br />
of iron believed to occur with aging and neurodegenerative disease. <br />
Phase observations from local susceptibility distributions,<br />
however, are corrupted by external biasfields, which <br />
may be identical to the sources of interest. Furthermore,<br />
limited observations of the phase makes the inversion ill-posed. We<br />
describe a variational approach to susceptibility estimation that<br />
incorporates a tissue-air atlas to resolve ambiguity in the forward model, while eliminating additional biasfields<br />
through application of the Laplacian. Results show qualitative improvement<br />
over two methods commonly used to infer underlying<br />
susceptibility values, and quantitative susceptibility estimates<br />
show better correlation with postmortem iron concentrations than<br />
competing methods.</div>Cpoynton