Projects:DTIModeling - Revision history

Ann Adams at 10:41, 14 May 2010

2010-05-14T10:41:50Z

Melonakos at 20:19, 11 May 2010

2010-05-11T20:19:03Z

Polina: /* Publications */

2009-09-29T18:24:24Z

Publications

Polina: /* Key Investigators */

2009-09-29T18:24:02Z

Key Investigators

Melonakos at 13:44, 28 August 2009

2009-08-28T13:44:28Z

Melonakos at 18:17, 26 August 2009

2009-08-26T18:17:10Z

Melonakos at 18:16, 26 August 2009

2009-08-26T18:16:50Z

Melonakos at 17:53, 13 July 2009

2009-07-13T17:53:05Z

Melonakos: /* Key Investigators */

2009-07-13T17:52:53Z

Key Investigators

Polina: /* Publications */

2009-05-13T22:16:52Z

Publications

@@ Line 7: / Line 7: @@
 = Description =
-We employ an expectation-maximization (EM) algorithm to cluster the trajectories in a Gamma mixture model context. The result of clustering is the probabilistic assignment of the fiber trajectories to each cluster and an estimate of the cluster parameters, i.e. spatial mean and variance, and point correspondences. The fiber bundles are modeled by the mean trajectory and its spatial variation. Point-by-point correspondence of the trajectories within a bundle is obtained by constructing a distance map and a label map from each cluster center at every iteration of the EM algorithm. This offers a time-efficient alternative to pairwise curve matching of all trajectories with respect to each cluster center.
+We employ an expectation-maximization (EM) algorithm to cluster the trajectories in a Gamma mixture model context. The result of clustering is the probabilistic assignment of the fiber trajectories to each cluster and an estimate of the cluster parameters, i.e., spatial mean and variance, and point correspondences. The fiber bundles are modeled by the mean trajectory and its spatial variation. Point-by-point correspondence of the trajectories within a bundle is obtained by constructing a distance map and a label map from each cluster center at every iteration of the EM algorithm. This offers a time-efficient alternative to pairwise curve matching of all trajectories with respect to each cluster center.
 The proposed method has the potential to benefit from an anatomical atlas of fiber tracts by incorporating it as prior information in the EM algorithm. The algorithm is also capable of handling outliers in a principled way. Here are some examples of modeling/clustering the bundles:
@@ Line 19: / Line 19: @@
 [[Image:cingulum.jpg|400px]][[Image:Gamma.jpg|250px]]
-Figure on the right illustrates the evolution of the Gamma distribution for the clusters of the first case shown the above figure. Convergence is achieved just after a few iterations of the EM algorithm.
+Figure on the right illustrates the evolution of the Gamma distribution for the clusters of the first case shown in the above figure. Convergence is achieved just after a few iterations of the EM algorithm.
 The proposed algorithm is being applied on several datasets. Below are two examples:
-'''Population Study on Patahogical Subjects'''
+'''Population Study on Pathological Subjects'''
 A population study on the cinglum bundle in controls and Schizophrenia cases:
@@ Line 43: / Line 43: @@
 = Key Investigators =
-* MIT: Mahnaz Maddah,Eric Grimson.
+* MIT: Mahnaz Maddah, Eric Grimson.
 * Harvard: Sandy Wells, Simon Warfield, C-F Westin, Martha E. Shenton, Marek Kubicki.

@@ Line 48: / Line 48: @@
 = Publications =
-*[http://www.na-mic.org/publications/pages/display?search=Projects%3ADTIModeling&submit=Search&words=all&title=checked&keywords=checked&authors=checked&abstract=checked&sponsors=checked&searchbytag=checked| NA-MIC Publications Database]
+*[http://www.na-mic.org/publications/pages/display?search=Projects%3ADTIModeling&submit=Search&words=all&title=checked&keywords=checked&authors=checked&abstract=checked&sponsors=checked&searchbytag=checked| NA-MIC Publications Databaseon Fiber Tract Modeling, Clustering, and Quantitative Analysis]
 [[Category: Shape Analysis]] [[Category:Schizophrenia]]

← Older revision		Revision as of 18:24, 29 September 2009
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	= Publications =		= Publications =
−	~~''In Print''~~

	*[http://www.na-mic.org/publications/pages/display?search=Projects%3ADTIModeling&submit=Search&words=all&title=checked&keywords=checked&authors=checked&abstract=checked&sponsors=checked&searchbytag=checked\| NA-MIC Publications Database]		*[http://www.na-mic.org/publications/pages/display?search=Projects%3ADTIModeling&submit=Search&words=all&title=checked&keywords=checked&authors=checked&abstract=checked&sponsors=checked&searchbytag=checked\| NA-MIC Publications Database]

@@ Line 43: / Line 43: @@
 = Key Investigators =
-* MIT: Mahnaz Maddah, Sandy Wells, Simon Warfield C-F Westin, and Eric Grimson.
+* MIT: Mahnaz Maddah,Eric Grimson.
 = Publications =

@@ Line 1: / Line 1: @@
-  Back to [[NA-MIC_Internal_Collaborations:DiffusionImageAnalysis|NA-MIC Collaborations]], [[Algorithm:MIT|MIT Algorithms]]
+  Back to [[Algorithm:MIT|MIT Algorithms]]
 __NOTOC__
 = DTI Modeling =

← Older revision		Revision as of 18:17, 26 August 2009
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	*[http://www.na-mic.org/publications/pages/display?search=Projects%3ADTIModeling&submit=Search&words=all&title=checked&keywords=checked&authors=checked&abstract=checked&sponsors=checked&searchbytag=checked\| NA-MIC Publications Database]		*[http://www.na-mic.org/publications/pages/display?search=Projects%3ADTIModeling&submit=Search&words=all&title=checked&keywords=checked&authors=checked&abstract=checked&sponsors=checked&searchbytag=checked\| NA-MIC Publications Database]
−
−	~~''In Press''~~



	[[Category: Shape Analysis]] [[Category:Schizophrenia]]		[[Category: Shape Analysis]] [[Category:Schizophrenia]]

← Older revision		Revision as of 22:16, 13 May 2009
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	''In Press''		''In Press''

−	* Mahnaz Maddah, Marek Kubicki, William M. Wells, Carl-Fredrik Westin, Martha E. Shenton and W. Eric L. Grimson, Findings in Schizophrenia by Tract-Oriented DT-MRI Analysis, to be presented in MICCAI 2008, NY, US.
−
−	* M. Maddah, L. Zollei, W. E. L. Grimson, W. M. Wells, Modeling of Anatomical Information in Clustering of White Matter Fiber Trajectories Using Dirichlet Distribution, to be presented at MMBIA 2008, Alaska, US.
−
−	* M. Maddah, L. Zollei, W. E. L. Grimson, C-F Westin, W. M. Wells, A Mathematical Framework for Incorporating Anatomical Knowledge in DT-MRI Analysis, ISBI 2008, Paris, France.
−
−	* M. Maddah, A. U. Mewes, H. Als, G. McAnulty, W. E. L. Grimson, and S. K. Warfield, Investigation of Neonate Brain Development Enabled by Tract-Oriented Quantification, ISMRM 2008, Toronto, Canada.


	[[Category: Shape Analysis]] [[Category:Schizophrenia]]		[[Category: Shape Analysis]] [[Category:Schizophrenia]]