Projects:DTIValidation - Revision history

Melonakos at 18:34, 2 April 2008

2008-04-02T18:34:11Z

Melonakos at 03:20, 6 January 2008

2008-01-06T03:20:11Z

Melonakos at 17:55, 22 December 2007

2007-12-22T17:55:23Z

Melonakos at 17:52, 22 December 2007

2007-12-22T17:52:31Z

Melonakos at 17:45, 22 December 2007

2007-12-22T17:45:36Z

Apreda at 19:10, 21 December 2007

2007-12-21T19:10:58Z

Apreda: /* Key Investigators */

2007-12-21T18:44:53Z

Key Investigators

Melonakos at 03:11, 21 December 2007

2007-12-21T03:11:14Z

Melonakos at 03:08, 21 December 2007

2007-12-21T03:08:32Z

Melonakos at 17:57, 12 December 2007

2007-12-12T17:57:09Z

← Older revision		Revision as of 18:34, 2 April 2008
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	* Irvine DBP 1: James Fallon, Martina Panzenboeck, Adrian Preda		* Irvine DBP 1: James Fallon, Martina Panzenboeck, Adrian Preda
	* Isomics Engineering: Steve Pieper		* Isomics Engineering: Steve Pieper
		+
		+	[[Category: Slicer]]

@@ Line 1: / Line 1: @@
-  Back to [[NA-MIC_Internal_Collaborations|NA-MIC Collaborations]], [[Algorithm:MIT|MIT Algorithms]], [[Algorithm:UNC|UNC Algorithms]], [[DBP1:Irvine|Irvine DBP 1]], [[Engineering:Isomics|Isomics Engineering]]
+  Back to [[NA-MIC_Internal_Collaborations:DiffusionImageAnalysis|NA-MIC Collaborations]], [[Algorithm:MIT|MIT Algorithms]], [[Algorithm:UNC|UNC Algorithms]], [[DBP1:Irvine|Irvine DBP 1]], [[Engineering:Isomics|Isomics Engineering]]
 __NOTOC__
 = DTI Validation =

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 {| cellpadding="10"
+| style="width:50%" | [[Image:MBIRNccred.png|500px]]
-| style="width:15%" | [[Image:MBIRNccred.png|500px]]
+| style="width:50%" | [[Image:MBIRNseedROIcc1.png|500px]]
-| style="width:85%" | [[Image:MBIRNseedROIcc1.png|500px]]
+|-
+||
 |}
 = Key Investigators =

← Older revision		Revision as of 17:52, 22 December 2007
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	Due to data format specificity Slicer validation was not feasible on Mori's dataset and the VETSA dataset. On the HUVA dataset Slicer produced a consistent error (abnormal thinness) in generating tracts with a major horizontal component. The HUVA coronal acquisition sequence and slice thickness (5 mmm) are likely contributors to this finding. Slicer produced only very short tracts on the Dartmouth dataset. Our preliminary conclusion is that Slicer is sensitive to the specifics of the diffusion sequence acquisition parameters. Future research is needed to establish critical values for diffusion sequence acquisition parameters that would allow diffusion data processing via Slicer. We solved compatibility issues pertaining to the NRRD format that initially precluded us from using Slicer on UC Irvine collected (Mosaic Siemens 3T Trio) datasets. To asses the Slicer reliability/validity in the same datasets we compared the results of 2 Slicer tracking approaches on the same dataset: a region of interest (ROI) based approach ''vs'' a point by point seeding approach. We concluded that the use of the fiber by fiber seeding ''vs'' deleting options complicates the creation of standard tracking algorhytms and might in fact results in decreased fiber tracking reliability/validity.		Due to data format specificity Slicer validation was not feasible on Mori's dataset and the VETSA dataset. On the HUVA dataset Slicer produced a consistent error (abnormal thinness) in generating tracts with a major horizontal component. The HUVA coronal acquisition sequence and slice thickness (5 mmm) are likely contributors to this finding. Slicer produced only very short tracts on the Dartmouth dataset. Our preliminary conclusion is that Slicer is sensitive to the specifics of the diffusion sequence acquisition parameters. Future research is needed to establish critical values for diffusion sequence acquisition parameters that would allow diffusion data processing via Slicer. We solved compatibility issues pertaining to the NRRD format that initially precluded us from using Slicer on UC Irvine collected (Mosaic Siemens 3T Trio) datasets. To asses the Slicer reliability/validity in the same datasets we compared the results of 2 Slicer tracking approaches on the same dataset: a region of interest (ROI) based approach ''vs'' a point by point seeding approach. We concluded that the use of the fiber by fiber seeding ''vs'' deleting options complicates the creation of standard tracking algorhytms and might in fact results in decreased fiber tracking reliability/validity.

		+	{\| cellpadding="10"
		+
		+	\| style="width:15%" \| [[Image:MBIRNccred.png\|500px]]
		+	\| style="width:85%" \| [[Image:MBIRNseedROIcc1.png\|500px]]
		+
		+	\|}
	= Key Investigators =		= Key Investigators =

@@ Line 1: / Line 1: @@
-Back to [[NA-MIC_Internal_Collaborations|NA-MIC Collaborations]], [[Algorithm:MIT|MIT Algorithms]], [[Algorithm:UNC|UNC Algorithms]], [[DBP1:Irvine|Irvine DBP 1]], [[Engineering:Isomics|Isomics Engineering]]
+ Back to [[NA-MIC_Internal_Collaborations|NA-MIC Collaborations]], [[Algorithm:MIT|MIT Algorithms]], [[Algorithm:UNC|UNC Algorithms]], [[DBP1:Irvine|Irvine DBP 1]], [[Engineering:Isomics|Isomics Engineering]]
 __NOTOC__
 = DTI Validation =

@@ Line 9: / Line 9: @@
 We have analyzed and validated 11 major tracts in one dataset (Susumu Mori's; 5 subjects) and using one tractography tool (DTI Studio). These were analyzed in several different labs and the quantitative (kappa values) validation was successful and a manuscript is presently in near-final form. We are now analyzing two different datasets (Susumu Mori, Dartmouth) using two tractography tools (DTI Studio, Slicer), quantitative and qualitative comparisons, and two investigators in Fallon's lab. We will also examine these with Guido Gerig's DTI tractography tool.
-DTI Studio validation: We have analyzed and validated 11 major tracts in one dataset (Susumu Mori's; 5 subjects) using one tractography tool (DTI Studio). These were analyzed in several different labs.  The quantitative (kappa values) validation was successful, and a manuscript has been submitted for publication.
+DTI Studio validation:
-Slicer validation: Due to data format specificity Slicer validation was not feasible on Mori's dataset and the VETSA dataset. On the HUVA dataset Slicer produced a consistent error (abnormal thinness) in generating tracts with a major horizontal component. The HUVA coronal acquisition sequence and slice thickness (5 mmm) are likely contributors to this finding. Slicer produced only very short tracts on the Dartmouth dataset. Our preliminary conclusion is that Slicer is sensitive to the specifics of the diffusion sequence acquisition parameters. Future research is needed to establish critical values for diffusion sequence acquisition parameters that would allow diffusion data processing via Slicer.
+Slicer validation:
 = Key Investigators =

@@ Line 1: / Line 1: @@
- Back to [[NA-MIC_Internal_Collaborations|NA-MIC Collaborations]], [[Algorithm:MIT|MIT Algorithms]], [[Algorithm:UNC|UNC Algorithms]], [[DBP1:Irvine|Irvine DBP 1]], [[Engineering:Isomics|Isomics Engineering]]
+Back to [[NA-MIC_Internal_Collaborations|NA-MIC Collaborations]], [[Algorithm:MIT|MIT Algorithms]], [[Algorithm:UNC|UNC Algorithms]], [[DBP1:Irvine|Irvine DBP 1]], [[Engineering:Isomics|Isomics Engineering]]
 __NOTOC__
 = DTI Validation =
@@ Line 17: / Line 17: @@
 * MIT Algorithms: Lauren O'Donnell, Raul San Jose
 * UNC Algorithms: Guido Gerig
-* Irvine DBP 1: James Fallon, Adrian Preda, Martina Panzenboeck
+* Irvine DBP 1: James Fallon, Martina Panzenboeck, Adrian Preda
 * Isomics Engineering: Steve Pieper