Projects:FractionalAnisotropyOfTheCorpusCallosumAndAnteriorCommissure - Revision history

Melonakos at 16:41, 12 December 2007

2007-12-12T16:41:57Z

Melonakos at 18:51, 27 November 2007

2007-11-27T18:51:25Z

Melonakos at 14:18, 4 September 2007

2007-09-04T14:18:24Z

Melonakos at 13:11, 4 September 2007

2007-09-04T13:11:29Z

Melonakos at 18:13, 3 September 2007

2007-09-03T18:13:54Z

Melonakos at 18:13, 3 September 2007

2007-09-03T18:13:36Z

Melonakos at 16:28, 21 August 2007

2007-08-21T16:28:10Z

Melonakos: NA-MIC/Projects/Diffusion Image Analysis/Fractional Anisotropy of the Corpus Callosum and Anterior Commissure moved to Projects:FractionalAnisotropyOfTheCorpusCallosumAndAnteriorCommissure

2007-08-21T03:38:12Z

NA-MIC/Projects/Diffusion Image Analysis/Fractional Anisotropy of the Corpus Callosum and Anterior Commissure moved to Projects:FractionalAnisotropyOfTheCorpusCallosumAndAnteriorCommissure

Andy: Update from Wiki

2006-12-18T19:30:41Z

Update from Wiki

New page

'''Objective:''' To use DTI to quantify the integrity of interhemispheric connectivity in schizophrenic patients, by measuring fractional anisotropy (FA) and other diffusion measures in both corpus collosum (CC) and anterior commissure (AC) fibers. To the best of our knowledge, no previous study has analyzed diffusion measures along the anterior commissure.

<br />'''Progress:''' We have implemented a scanning protocol by which we obtain several midline sagittal slices, allowing high resolution data of both the midsagittal corpus callosum and the anterior commisure. Preliminary results (methods currently being improved) indicate decreased FA in the midsagittal corpus callosum in schizophrenics, and decreased overall diffusivity in both the corpus callosum and anterior commisure. We are currently utilizing fiber tracking in these structures to calculate FA (and other diffusion measures) along both CC and AC fibers. We are considering using smoothed data to create these fibers. We are also using automatic clustering to separate anatomically similar fibers, and compare diffusion measures along fibers extending to different brain regions.

<br />'''Key Investigators:'''

* Marek Kubicki, BWH
* Lauren O'Donnell, MIT
* Mark Dreusicke, BWH
* Doug Markant, BWH
* Carl-Fredrik Westin, BWH
* Martha Shenton, BWH

<br />'''Links:'''

* Progress on improving the method used to create corpus callosum ROIs [[DBP:Harvard:Software:Bugs:Corpus_Callosum|'''here''']].
* Images of corpus callosum fibers using smoothed vs. unsmoothed data [[DBP:Harvard:Software:Bugs:Corpus_Callosum_Fibers|'''here''']].

@@ Line 1: / Line 1: @@
   Back to [[NA-MIC_Collaborations|NA-MIC_Collaborations]], [[Algorithm:MIT|MIT Algorithms]]
+__NOTOC__
 = Fractional Anisotropy of the Corpus Callosum and Anterior Commissure =

@@ Line 1: / Line 1: @@
   Back to [[NA-MIC_Collaborations|NA-MIC_Collaborations]], [[Algorithm:MIT|MIT Algorithms]]
-'''Objectives'''
+= Fractional Anisotropy of the Corpus Callosum and Anterior Commissure =
 To use DTI to quantify the integrity of interhemispheric connectivity in schizophrenic patients, by measuring fractional anisotropy (FA) and other diffusion measures in both corpus collosum (CC) and anterior commissure (AC) fibers. To the best of our knowledge, no previous study has analyzed diffusion measures along the anterior commissure.
-'''Progress'''
+= Description =
 We have implemented a scanning protocol by which we obtain several midline sagittal slices, allowing high resolution data of both the midsagittal corpus callosum and the anterior commisure. Preliminary results (methods currently being improved) indicate decreased FA in the midsagittal corpus callosum in schizophrenics, and decreased overall diffusivity in both the corpus callosum and anterior commisure. We are currently utilizing fiber tracking in these structures to calculate FA (and other diffusion measures) along both CC and AC fibers. We are considering using smoothed data to create these fibers. We are also using automatic clustering to separate anatomically similar fibers, and compare diffusion measures along fibers extending to different brain regions.
-''References''
+= Key Investigators =
 * BWH: Marek Kubicki, Carl-Fredrik Westin, Mark Dreusicke, Doug Markant, Martha Shenton
 * MIT: Lauren O'Donnell
-'''Links'''
+= Links =
 * Progress on improving the method used to create corpus callosum ROIs [[DBP:Harvard:Software:Bugs:Corpus_Callosum|'''here''']].
 * Images of corpus callosum fibers using smoothed vs. unsmoothed data [[DBP:Harvard:Software:Bugs:Corpus_Callosum_Fibers|'''here''']].

@@ Line 3: / Line 3: @@
   Back to [[NA-MIC_Collaborations|NA-MIC_Collaborations]], [[Algorithm:MIT|MIT Algorithms]]
-'''Objective'''
+'''Objectives'''
 To use DTI to quantify the integrity of interhemispheric connectivity in schizophrenic patients, by measuring fractional anisotropy (FA) and other diffusion measures in both corpus collosum (CC) and anterior commissure (AC) fibers. To the best of our knowledge, no previous study has analyzed diffusion measures along the anterior commissure.
-<br />'''Progress'''
+'''Progress'''
 We have implemented a scanning protocol by which we obtain several midline sagittal slices, allowing high resolution data of both the midsagittal corpus callosum and the anterior commisure. Preliminary results (methods currently being improved) indicate decreased FA in the midsagittal corpus callosum in schizophrenics, and decreased overall diffusivity in both the corpus callosum and anterior commisure. We are currently utilizing fiber tracking in these structures to calculate FA (and other diffusion measures) along both CC and AC fibers. We are considering using smoothed data to create these fibers. We are also using automatic clustering to separate anatomically similar fibers, and compare diffusion measures along fibers extending to different brain regions.
-<br />'''Key Investigators'''
+''References''
-* Marek Kubicki, BWH
+'''Key Investigators'''
-<br />'''Links'''
+* BWH: Marek Kubicki, Carl-Fredrik Westin, Mark Dreusicke, Doug Markant, Martha Shenton
 * Progress on improving the method used to create corpus callosum ROIs [[DBP:Harvard:Software:Bugs:Corpus_Callosum|'''here''']].
 * Images of corpus callosum fibers using smoothed vs. unsmoothed data [[DBP:Harvard:Software:Bugs:Corpus_Callosum_Fibers|'''here''']].

@@ Line 1: / Line 1: @@
 = Fractional Anisotropy of the Corpus Callosum and Anterior Commissure =
-  Back to [[NA-MIC_Collaborations|NA-MIC_Collaborations]]
+  Back to [[NA-MIC_Collaborations|NA-MIC_Collaborations]], [[Algorithm:MIT|MIT Algorithms]]
 '''Objective'''

← Older revision		Revision as of 18:13, 3 September 2007
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−	Fractional Anisotropy of the Corpus Callosum and Anterior Commissure	+	= Fractional Anisotropy of the Corpus Callosum and Anterior Commissure =

	Back to [[NA-MIC_Collaborations\|NA-MIC_Collaborations]]		Back to [[NA-MIC_Collaborations\|NA-MIC_Collaborations]]

← Older revision		Revision as of 16:28, 21 August 2007
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		+	Back to [[NA-MIC_Collaborations\|NA-MIC_Collaborations]]
		+
	'''Objective:''' To use DTI to quantify the integrity of interhemispheric connectivity in schizophrenic patients, by measuring fractional anisotropy (FA) and other diffusion measures in both corpus collosum (CC) and anterior commissure (AC) fibers. To the best of our knowledge, no previous study has analyzed diffusion measures along the anterior commissure.		'''Objective:''' To use DTI to quantify the integrity of interhemispheric connectivity in schizophrenic patients, by measuring fractional anisotropy (FA) and other diffusion measures in both corpus collosum (CC) and anterior commissure (AC) fibers. To the best of our knowledge, no previous study has analyzed diffusion measures along the anterior commissure.

← Older revision	Revision as of 03:38, 21 August 2007
(No difference)