Difference between revisions of "Projects/Diffusion/2007 Project Week Contrasting Tractography Measures/ROI Definitions"
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== Internal Capsule (IC) == | == Internal Capsule (IC) == | ||
+ | Connects thalamus with frontal lobe | ||
+ | Involved in executive functions and working memory, both of these cognitive skills are abnormal in schizophrenia. | ||
+ | |||
'''ROI1''' | '''ROI1''' | ||
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==Uncinate Fasciculus (UNC)== | ==Uncinate Fasciculus (UNC)== | ||
+ | '''Connects temporal pole and orbito-frontal gyrus. <br> | ||
+ | Involved in episodic memory, verbal learning, and emotion. <br> | ||
+ | Related to affective flattening and episodic memory dysfunctions in schizophrenia.''' <br> | ||
[[Image:Uncinate.jpg|thumb|right|300px|Uncinate Fasciculus]] | [[Image:Uncinate.jpg|thumb|right|300px|Uncinate Fasciculus]] | ||
The most prominant (central) slice of the fornix was identified using a sagittal view (Fig. 5), and the ROI1s and ROI2s were drawn on the coronal slice adjacent to the most anterior point of the fornix (Fig. 6). | The most prominant (central) slice of the fornix was identified using a sagittal view (Fig. 5), and the ROI1s and ROI2s were drawn on the coronal slice adjacent to the most anterior point of the fornix (Fig. 6). |
Revision as of 03:51, 9 August 2007
Home < Projects < Diffusion < 2007 Project Week Contrasting Tractography Measures < ROI Definitions
Seed points were defined using a two ROIs approach. Each ROI was drawn on FA and color by orientation maps according to the criteria defined below: ContentsInternal Capsule (IC)Connects thalamus with frontal lobe Involved in executive functions and working memory, both of these cognitive skills are abnormal in schizophrenia. ROI1 The inferior boundary of ROI1 was defined by an axial slice containing the anterior commisure (Fig.1). The left and right ROI1s were drawn on a coronal slice containing the anterior commisure, on each side of the midsagittal line (Fig.2). The superior boundary of each ROI1 was defined by the caudate/putamen line |
ROI2 The most anterior coronal slice of the corpus collosum was selected using a sagittal view (Fig 3), and the ROI2s were defined by the whole sections of the left and right hemispheres of the brain (Fig 4). |
The color coding of the resulting ROIs is as follows:
Uncinate Fasciculus (UNC)Connects temporal pole and orbito-frontal gyrus. The most prominant (central) slice of the fornix was identified using a sagittal view (Fig. 5), and the ROI1s and ROI2s were drawn on the coronal slice adjacent to the most anterior point of the fornix (Fig. 6).
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The color coding of the resulting ROIs is as follows:
FornixROI 1 was drawn on the sagittal slice, 5 slices superior to the anterior commisure (Fig. 8 & 10). ROI 2 was drawn on a coronal slice where the crux of the fornix was present. It was not always the same slice for both sides (Fig. 9 & 11).
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The color coding of the resulting ROIs is as follows:
Arcuate FasciculusThese labelmaps ('caseD00XXX-FS-arcuate-final.nhdr') were created using automatic gray matter parcellation in Freesurfer and coregistered in Slicer to corresponding DTI dataset. The labelmaps were dilated in Slicer to increase coverage of gray matter.
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The color coding of the resulting ROIs is as follows:
Cingulum BundleROI 1) A coronal plane in the most anterior point of the corpus callosum was selected using the mid-saggital plane (Fig.18), and the left and right ROI1s were drawn on the superior side of the corpus callosum (Fig.15) ROI 2) & ROI 3) The first coronal slice where the left and right corpus connect was selected: the left and right ROI2s were drawn on the superior side of the corpus and the left and right ROI3s were drawn on the inferior side of the corpus (Fig. 16 & 18) ROI 4) The first coronal slice showing where the middle cerebellar peduncle was slected, and the left and right ROI4s were drawn(Fig. 17 & 19)
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The color coding of the resulting ROIs is as follows:
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