2017 Winter Project Week/PkModeling

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  Projects List

Key Investigators

• Andrew Beers, Jayashree Kalpathy-Cramer, MGH
• Jim Miller, GE

Project Description

Objective	Approach and Plan	Progress and Next Steps
PkModeling, a Slicer module meant to derive DCE pharmokinetic parameters via the two and three parameter Tofts model, has not had perfect accuracy on phantoms for the Tofts model. We intend to troubleshoot and address these errors, which we have determined from our previous research to be problems with the implementations of the Tofts model. Make the module more usable and/or intuitive to casual users. Although it may be a larger Slicer infrastructure project, add support to Slicer for 4D Niftis, the main file format of our lab.	Debug the module with several test cases and deconstruct the models steps to see where error is introduced to its calculations. Model UI off of successful modules, and seek advice from attendants of Project Week. Probe conversion between MultiVolumes and 4D Nifti files.