2008 Summer Project Week:DWI-DTI PrepTools

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Key Investigators

• UNC: Heather Cody Hazlett, Martin Styner, Zhexing Liu
• Utah: Casey Goodlett, Guido Gerig, Tom Fletcher

Objective

We are developing a tool for preparing diffusion weighted and diffusion tensor image data.

Details of the tool functionality were discussed thus far between UNC and Utah. The discussions have been summarized in it's event page:

• "protocol" based execution via parameter files.
  • Parameter files contain all the settings/preferences/options
• Handles the conversion of DICOM data to volumetric image formats (NRRD)
• Automated quality control, corrects/rejects data, and provides a reporting facility.
  • Motion correction
  • Eddy current correction
  • Interpolation of data
  • Quality Control
    • Rejection of interslice brightness
    • Local plausibility check with reconstructed DTI
    • FA/MD histogram comparison with atlas
    • Local dot product of principal direction with atlas
    • Full brain tracking for possible flips, permutations of direction axes
    • Focus QC on white matter only
• DTI data is generated, as well as FA/MD etc

Approach, Plan

The tool will allow a "protocol" based execution via parameter files. The parameter files contain all the settings/preferences/options and this file can be created using the tool's GUI. This tool will handle the conversion of DICOM data to volumetric image formats (NRRD), perform automated quality control, correct data if possible, possibly reject parts of the data and provide a reporting facility.

Progress