Difference between revisions of "2009 Summer Project Week 4D Gated US In Slicer"

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(Created page with '__NOTOC__ <gallery> Image:PW2009-v3.png|Project Week Main Page Image:genuFAp.jpg|Scatter plot of the original FA data through the genu of the corpus ...')
 
 
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__NOTOC__
 
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Image:PW2009-v3.png|[[2009_Summer_Project_Week|Project Week Main Page]]
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Image:PW2009-v3.png|[[2009_Summer_Project_Week#Projects|Project Week Main Page]]
Image:genuFAp.jpg|Scatter plot of the original FA data through the genu of the corpus callosum of a normal brain.
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Image:3DUSReconstructionSchematic.png|Schematic of 3D ultrasound reconstruction
Image:genuFA.jpg|Regression of FA data; solid line represents the mean and dotted lines the standard deviation.
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Image:GatedUSReconstructionSchematic.png|Schematic of gated (4D) ultrasound reconstruction
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Image:GatedUSReconstruction rotationalTEE_0R-R.jpg|Example reconstructed ultrasound volume of a porcine heart, at 0% R-R
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Image:GatedUSReconstruction rotationalTEE_50R-R.jpg|Example reconstructed ultrasound volume of a porcine heart, at 50% R-R
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==Instructions for Use of this Template==
 
#Please create a new wiki page with an appropriate title for your project using the convention Project/<Project Name>
 
#Copy the entire text of this page into the page created above
 
#Link the created page into the list of projects for the project event
 
#Delete this section from the created page
 
#Send an email to tkapur at bwh.harvard.edu if you are stuck
 
  
 
==Key Investigators==
 
==Key Investigators==
* UNC: Isabelle Corouge, Casey Goodlett, Guido Gerig
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* Robarts Research Institute / University of Western Ontario: Danielle Pace
* Utah: Tom Fletcher, Ross Whitaker
 
  
 
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<h3>Objective</h3>
 
<h3>Objective</h3>
We are developing methods for analyzing diffusion tensor data along fiber tracts. The goal is to be able to make statistical group comparisons with fiber tracts as a common reference frame for comparison.
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The objective of this project is to enable gated four-dimensional ultrasound reconstruction in Slicer3.
 
 
 
 
 
 
  
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We have previously written and validated software that performs 4D ultrasound reconstruction from a tracked 2D probe in real-time (Pace et al, SPIE 2009).  This allows the user to interact with the reconstructed time series of 3D volumes as they are being acquired and to adjust the acquisition process as necessary.  The user-interface for the reconstruction software has been implemented within the [http://www.atamai.com Atamai Viewer] framework.  During the project week, we will integrate it into Slicer3.
  
  
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<h3>Approach, Plan</h3>
 
<h3>Approach, Plan</h3>
  
Our approach for analyzing diffusion tensors is summarized in the IPMI 2007 reference belowThe main challenge to this approach is <foo>.
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We plan to interface the reconstruction software with Slicer3 using the SynchroGrab framework described by (Boisvert et al, MICCAI 2008)A command-line interface and a calibration file will allow the user to specify the reconstruction parameters.  While the gated reconstruction is performed, the resulting time series of volumes will be transferred to Slicer3 using the OpenIGTLink protocol for interactive visualization.
  
Our plan for the project week is to first try out <bar>,...
 
  
 
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<h3>Progress</h3>
 
<h3>Progress</h3>
Software for the fiber tracking and statistical analysis along the tracts has been implemented. The statistical methods for diffusion tensors are implemented as ITK code as part of the [[NA-MIC/Projects/Diffusion_Image_Analysis/DTI_Software_and_Algorithm_Infrastructure|DTI Software Infrastructure]] project. The methods have been validated on a repeated scan of a healthy individual. This work has been published as a conference paper (MICCAI 2005) and a journal version (MEDIA 2006). Our recent IPMI 2007 paper includes a nonparametric regression method for analyzing data along a fiber tract.
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* Discussions with Noby Hata pointed us to an extension of the SynchroGrab code base previously written by Jan Gumprecht, and so we decided to use this as our starting point.
 
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* During the project week, we began modifying this software to work with our real-time 4D US reconstruction classes.
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* To visualize the 4D dataset within Slicer3, Junichi Tokuda's [http://www.na-mic.org/Wiki/index.php/2009_Summer_Project_Week_4D_Imaging 4D imaging module] will be used to toggle between the different 3D volumes and to play a cine loop of the entire dataset.
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* Further work includes testing the software in the lab with actual ultrasound and tracking devices.
  
 
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==References==
 
==References==
*Fletcher P, Tao R, Jeong W, Whitaker R. [http://www.na-mic.org/publications/item/view/634 A volumetric approach to quantifying region-to-region white matter connectivity in diffusion tensor MRI.] Inf Process Med Imaging. 2007;20:346-358. PMID: 17633712.
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*Pace DF, Wiles AD, Moore J, Wedlake C, Gobbi DG, Peters TM, [http://spie.org/x648.html?product_id=813705 Validation of four-dimensional ultrasound for targetting in minimally-invasive beating-heart surgery], Proceedings of SPIE Medical Imaging: Visualization, Image-Guided Procedures and Modeling, 2009.
* Corouge I, Fletcher P, Joshi S, Gouttard S, Gerig G. [http://www.na-mic.org/publications/item/view/292 Fiber tract-oriented statistics for quantitative diffusion tensor MRI analysis.] Med Image Anal. 2006 Oct;10(5):786-98. PMID: 16926104.
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*Boisvert J, Gobbi DG, Vikal S, Rohling R, Fichtinger G, Abolmaesumi P, [http://www.midasjournal.org/browse/publication/618 An open-source solution for interactive acquisition, processing and transfer of interventional ultrasound images], Workshop on Systems and Architectures for Computer Assisted Interventions, MICCAI 2008.
* Corouge I, Fletcher P, Joshi S, Gilmore J, Gerig G. [http://www.na-mic.org/publications/item/view/1122 Fiber tract-oriented statistics for quantitative diffusion tensor MRI analysis.] Int Conf Med Image Comput Comput Assist Interv. 2005;8(Pt 1):131-9. PMID: 16685838.
 
* Goodlett C, Corouge I, Jomier M, Gerig G, A Quantitative DTI Fiber Tract Analysis Suite, The Insight Journal, vol. ISC/NAMIC/ MICCAI Workshop on Open-Source Software, 2005, Online publication: http://hdl.handle.net/1926/39 .
 
  
 
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Latest revision as of 13:27, 26 June 2009

Home < 2009 Summer Project Week 4D Gated US In Slicer

Key Investigators

  • Robarts Research Institute / University of Western Ontario: Danielle Pace

Objective

The objective of this project is to enable gated four-dimensional ultrasound reconstruction in Slicer3.

We have previously written and validated software that performs 4D ultrasound reconstruction from a tracked 2D probe in real-time (Pace et al, SPIE 2009). This allows the user to interact with the reconstructed time series of 3D volumes as they are being acquired and to adjust the acquisition process as necessary. The user-interface for the reconstruction software has been implemented within the Atamai Viewer framework. During the project week, we will integrate it into Slicer3.


Approach, Plan

We plan to interface the reconstruction software with Slicer3 using the SynchroGrab framework described by (Boisvert et al, MICCAI 2008). A command-line interface and a calibration file will allow the user to specify the reconstruction parameters. While the gated reconstruction is performed, the resulting time series of volumes will be transferred to Slicer3 using the OpenIGTLink protocol for interactive visualization.


Progress

  • Discussions with Noby Hata pointed us to an extension of the SynchroGrab code base previously written by Jan Gumprecht, and so we decided to use this as our starting point.
  • During the project week, we began modifying this software to work with our real-time 4D US reconstruction classes.
  • To visualize the 4D dataset within Slicer3, Junichi Tokuda's 4D imaging module will be used to toggle between the different 3D volumes and to play a cine loop of the entire dataset.
  • Further work includes testing the software in the lab with actual ultrasound and tracking devices.

References