2009 Summer Project Week fusion of MRI with voltage mapping
Key Investigators
- Dana C. Peters PhD, and Jason Taclas, MS, Beth Israel Deaconess Medical Center
Objective
Scar in the left atrium can be visualized using the cardiac MR late gadolinium enhancement technique. It can also be detected as low electrical voltages by invasive electrophysiology (EP) mapping systems, e.g CARTO maps. We wish to correlate the EP maps with cardiac MR images, by registering the two representations of scar, and displaying the voltage as a 3D color map. Figure 1 compares a CARTO map of the left atrium to an image of the left atrium, demonstrating the relationship between low voltage by EP, and enhancement by Cardiac MR.
Approach, Plan
- Display surfaces using VTK/ITK tool already developed, with color coding to indicate voltage, with registered scar data. Extract registered voltage data to display on MR images.<foo>.
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Progress
Software for the fiber tracking and statistical analysis along the tracts has been implemented. The statistical methods for diffusion tensors are implemented as ITK code as part of the DTI Software Infrastructure project. The methods have been validated on a repeated scan of a healthy individual. This work has been published as a conference paper (MICCAI 2005) and a journal version (MEDIA 2006). Our recent IPMI 2007 paper includes a nonparametric regression method for analyzing data along a fiber tract.
References
- Taclas J, Wylie J, Nezafat R, Josephson M, Manning WJ, Peters DC. Correlation of Left Atrial Scar due to Pulmonary Vein Ablation with Recorded Ablation Sites. In:Journal of Cardiovascular MR. Los Angeles, CA, 2008.
- Peters DC, Wylie JV, Hauser TH, et al. Detection of pulmonary vein and left atrial scar after catheter ablation with three-dimensional navigator-gated delayed enhancement MR imaging: initial experience. Radiology 2007; 243:690-695.
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