2009 Winter Project Week:LocalCorticalThicknessPipeline

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Key Investigators

  • UNC: Clement Vachet, Martin Styner, Heather Cody Hazlett, Marc Niethammer
  • GE: Jim Miller


Objective

We are developing an end-to-end application within Slicer3 allowing individual and group analysis of local cortical thickness.

Such a workflow applied to the young brain (2-4 years old) is our goal in order to start a longitudinal study of early brain development in autism (UNC DBP).

See our Roadmap for more details.

Approach, Plan

Our plan for the project week is to finish the pipeline and perform the analysis on a small dataset.

Progress

Software for the registration between electrophysiology Carto data and the MR angiogram has been implemented, using the ITK/VTK platform (see ISMRM 2008 abstract, Taclas et al, and figure above). This week we wrote code to quantitatively determine the distances between each ablation location, and the closest region of scar, and to determine the distances between each pixel of scar, and the nearest ablation point. Therefore we accomplished our goal!


References