2011 Summer Project Week Non-rigid inter-patient registration of bone masks derived from CT for Head and Neck Cancer Radiation Therapy

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  Projects List

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Key Investigators

• Georgia Tech: Ivan Kolesov, Yi Gao, and Allen Tannenbaum
• MGH: Gregory Sharp

Objective

• Obtain segmentations of a number of organs in the head, neck region.

Approach, Plan

• Segmentation based on intensity alone is insufficient => does not lead to robust performance
• We require shape information to constrain the problem
• An atlas of organs must be created
• We will explore deformable registration techniques applied to our data
• Also, we will consider possible sparse representations of our imagery to simplify the problem

Progress

• Tested pipeline to perform atlas based segmentation
• Used BRAINSFIT to perform Bspline registration of patient bone masks
• First results are promising
• Next Steps:
  • Create patient masks to remove fixtures
  • Automate the segmentation pipeline and use multiple atlases
  • Use the atlases as initializations as opposed to final segmentations

Delivery Mechanism

This work will be delivered to the NA-MIC Kit as a command line module.

References