Difference between revisions of "2011 Winter Project Week:The Vascular Modeling Toolkit in 3D Slicer"

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<gallery>
 
<gallery>
 
Image:PW-SLC2011.png|[[2011_Winter_Project_Week#Projects|Projects List]]
 
Image:PW-SLC2011.png|[[2011_Winter_Project_Week#Projects|Projects List]]
Image:genuFAp.jpg|Scatter plot of the original FA data through the genu of the corpus callosum of a normal brain.
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Image:Slicervmtk logo.png|VMTK in 3D Slicer
Image:genuFA.jpg|Regression of FA data; solid line represents the mean and dotted lines the standard deviation.
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Image:Vesselenhancement.png|Enhancing vasculature structures
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Image:Easylevelsetsegmentation.png|Level-Set segmentation
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Image:Centerlines.png|Computation of Centerlines
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Image:Networkextraction.png|Network extraction of vessel trees
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Image:Branchsplitting.png|Branchsplitting
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Image:Anim.gif|The new parameter widget for VMTKVesselness4
 
</gallery>
 
</gallery>
  
 
==Key Investigators==
 
==Key Investigators==
 
* UPenn: Daniel Haehn, Kilian Pohl
 
* UPenn: Daniel Haehn, Kilian Pohl
* Mario Negri Institute, Italy: Luca Antiga
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* Rutgers: M. Gokhan Uzunbas
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* [http://www.orobix.com Orobix], Italy: Luca Antiga
 
* SPL: Steve Pieper, Ron Kikinis
 
* SPL: Steve Pieper, Ron Kikinis
  
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The Vascular Modeling Toolkit ([http://www.vmtk.org VMTK]) is a collection of libraries and tools for 3D reconstruction, geometric analysis, mesh generation and surface data analysis for image-based modeling of blood vessels.  
 
The Vascular Modeling Toolkit ([http://www.vmtk.org VMTK]) is a collection of libraries and tools for 3D reconstruction, geometric analysis, mesh generation and surface data analysis for image-based modeling of blood vessels.  
  
Several 3D Slicer extensions exist providing VMTK functionality in Slicer3. We want to investigate how to include the VMTK in 3D Slicer functionality in the upcoming Slicer4 application.
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Several 3D Slicer extensions already exist and provide VMTK functionality in Slicer3.  
 
 
 
 
  
 
</div>
 
</div>
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<h3>Approach, Plan</h3>
 
<h3>Approach, Plan</h3>
 
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We want to investigate how to include the VMTK in 3D Slicer functionality in the upcoming Slicer4 application. This should include several enhancements to the existing user interfaces.
Our approach for analyzing diffusion tensors is summarized in the IPMI 2007 reference below. The main challenge to this approach is <foo>.
 
 
 
Our plan for the project week is to first try out <bar>,...
 
 
 
 
</div>
 
</div>
  
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<h3>Progress</h3>
 
<h3>Progress</h3>
Software for the fiber tracking and statistical analysis along the tracts has been implemented. The statistical methods for diffusion tensors are implemented as ITK code as part of the [[NA-MIC/Projects/Diffusion_Image_Analysis/DTI_Software_and_Algorithm_Infrastructure|DTI Software Infrastructure]] project. The methods have been validated on a repeated scan of a healthy individual. This work has been published as a conference paper (MICCAI 2005) and a journal version (MEDIA 2006). Our recent IPMI 2007 paper includes a nonparametric regression method for analyzing data along a fiber tract.
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'''Project Week Update:'''
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Unfortunately, we did not have as much time as we liked to spend on this project. Nevertheless, we created a QT widget to optimize the selection of user-defined parameters for vessel enhancement. The new widget will be part of the upcoming first VMTK module for Slicer4 called VMTKVesselness4.
  
 +
We plan to investigate if the integration of the new widget in CTK makes sense.
  
 
</div>
 
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##Built-in
 
##Built-in
 
##Extension -- commandline
 
##Extension -- commandline
##Extension -- loadable
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##Extension -- loadable [X]
 
#Other (Please specify)
 
#Other (Please specify)
  
 
==References==
 
==References==
*Fletcher P, Tao R, Jeong W, Whitaker R. [http://www.na-mic.org/publications/item/view/634 A volumetric approach to quantifying region-to-region white matter connectivity in diffusion tensor MRI.] Inf Process Med Imaging. 2007;20:346-358. PMID: 17633712.
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* Antiga L, Piccinelli M, Botti L, Ene-Iordache B, Remuzzi A and Steinman DA. An image-based modeling framework for patient-specific computational hemodynamics. Medical and Biological Engineering and Computing, 46: 1097-1112, Nov 2008.
* Corouge I, Fletcher P, Joshi S, Gouttard S, Gerig G. [http://www.na-mic.org/publications/item/view/292 Fiber tract-oriented statistics for quantitative diffusion tensor MRI analysis.] Med Image Anal. 2006 Oct;10(5):786-98. PMID: 16926104.
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* D. Hähn. Integration of the vascular modeling toolkit in 3d slicer. SPL, 04 2009. Available online at http://www.spl.harvard.edu/publications/item/view/1728.
* Corouge I, Fletcher P, Joshi S, Gilmore J, Gerig G. [http://www.na-mic.org/publications/item/view/1122 Fiber tract-oriented statistics for quantitative diffusion tensor MRI analysis.] Int Conf Med Image Comput Comput Assist Interv. 2005;8(Pt 1):131-9. PMID: 16685838.
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* D. Hähn. Centerline Extraction of Coronary Arteries in 3D Slicer using VMTK based Tools. Master's Thesis. Department of Medical Informatics, University of Heidelberg, Germany. Feb 2010.
* Goodlett C, Corouge I, Jomier M, Gerig G, A Quantitative DTI Fiber Tract Analysis Suite, The Insight Journal, vol. ISC/NAMIC/ MICCAI Workshop on Open-Source Software, 2005, Online publication: http://hdl.handle.net/1926/39 .
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* Piccinelli M, Veneziani A, Steinman DA, Remuzzi A, Antiga L (2009) A framework for geometric analysis of vascular structures: applications to cerebral aneurysms. IEEE Trans Med Imaging. In press.
  
 
</div>
 
</div>

Latest revision as of 15:37, 14 January 2011

Home < 2011 Winter Project Week:The Vascular Modeling Toolkit in 3D Slicer

Key Investigators

  • UPenn: Daniel Haehn, Kilian Pohl
  • Rutgers: M. Gokhan Uzunbas
  • Orobix, Italy: Luca Antiga
  • SPL: Steve Pieper, Ron Kikinis

Objective

The Vascular Modeling Toolkit (VMTK) is a collection of libraries and tools for 3D reconstruction, geometric analysis, mesh generation and surface data analysis for image-based modeling of blood vessels.

Several 3D Slicer extensions already exist and provide VMTK functionality in Slicer3.

Approach, Plan

We want to investigate how to include the VMTK in 3D Slicer functionality in the upcoming Slicer4 application. This should include several enhancements to the existing user interfaces.

Progress

Project Week Update: Unfortunately, we did not have as much time as we liked to spend on this project. Nevertheless, we created a QT widget to optimize the selection of user-defined parameters for vessel enhancement. The new widget will be part of the upcoming first VMTK module for Slicer4 called VMTKVesselness4.

We plan to investigate if the integration of the new widget in CTK makes sense.

Delivery Mechanism

This work will be delivered to the NA-MIC Kit as a (please select the appropriate options by noting YES against them below)

  1. ITK Module
  2. Slicer Module
    1. Built-in
    2. Extension -- commandline
    3. Extension -- loadable [X]
  3. Other (Please specify)

References

  • Antiga L, Piccinelli M, Botti L, Ene-Iordache B, Remuzzi A and Steinman DA. An image-based modeling framework for patient-specific computational hemodynamics. Medical and Biological Engineering and Computing, 46: 1097-1112, Nov 2008.
  • D. Hähn. Integration of the vascular modeling toolkit in 3d slicer. SPL, 04 2009. Available online at http://www.spl.harvard.edu/publications/item/view/1728.
  • D. Hähn. Centerline Extraction of Coronary Arteries in 3D Slicer using VMTK based Tools. Master's Thesis. Department of Medical Informatics, University of Heidelberg, Germany. Feb 2010.
  • Piccinelli M, Veneziani A, Steinman DA, Remuzzi A, Antiga L (2009) A framework for geometric analysis of vascular structures: applications to cerebral aneurysms. IEEE Trans Med Imaging. In press.