2012 Summer Project Week:4D shape analysis

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  Projects List

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  Shape evolution of sub-cortical structures. Color denotes magnitude of velocity.

Key Investigators

• Utah: James Fishbaugh, Marcel Prastawa, Guido Gerig

Objective

We are interested in detecting and quantifying shape changes associated with the progression of Huntington's disease. Preliminary experiments on sub-cortical structures in HD from previous project weeks were intended as a test of our methodology. In order to have an impact moving forward, our tools needs to be robust, easy to use, and available as open-source software. The objective is to improve upon our research code base, leveraging open source libraries.

Approach, Plan

Consider available software design decisions and begin improving research code.

Progress

References

• Fishbaugh, J., Prastawa, M., Durrleman, S., Piven, J., Gerig G. Analysis of Longitudinal Shape Variability via Subject Specific Growth Modeling. Proc. of Medical Image Computing and Computer Assisted Intervention (MICCAI '12). (to appear),

• Fishbaugh, J., Durrleman, S., Piven, J., Gerig, G. A Framework for Longitudinal Data Analysis via Shape Regression . SPIE Medical Imaging 2012: Image Processing. Vol. 8314.

• Fishbaugh, J., Durrleman, S., Gerig, G. Estimation of Smooth Growth Trajectories with Controlled Acceleration from Time Series Shape Data. Proc. of Medical Image Computing and Computer Assisted Intervention (MICCAI '11).