Difference between revisions of "2012 Winter Project Week: Continuous 4D shapes"

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<!-- [[Image:HD_all_sub_cort_volume.png|thumb|800px|center|'''Fig 1.''' Volume of sub-cortical segmentations for 6 HD subjects. ]] -->
 
<!-- [[Image:HD_all_sub_cort_volume.png|thumb|800px|center|'''Fig 1.''' Volume of sub-cortical segmentations for 6 HD subjects. ]] -->

Revision as of 05:35, 13 January 2012

Home < 2012 Winter Project Week: Continuous 4D shapes

Key Investigators

James Fishbaugh, Hans Johnson, Guido Gerig

Objective

During the 2011 summer project week, we applied our shape regression framework to sub-cortical shapes from a single HD subject. For this project, we plan to begin processing multiple subjects. We would like to compare the trajectories of various measurements of interest, such as volume, across subjects at different stages of disease progression.

Approach, Plan

  • Estimate continuous trajectories for sub-cortical structures for multiple subjects
  • Investigate volume changes between subjects at different stages of disease progression
  • Explore shape evolution for other potentially significant measurements

Progress

HD Subjects

10001

10002

10010

10018

10022

10027

Control Subjects

10003

10004

10009

10014

10016

10017

10059


References

  • Fishbaugh, J., Durrleman, S., Gerig, G. A Framework for Longitudinal Data Analysis via Shape Regression . SPIE Medical Imaging 2012: Image Processing. Vol. 8314. (To appear)
  • Fishbaugh, J., Durrleman, S., Gerig, G. Estimation of Smooth Growth Trajectories with Controlled Acceleration from Time Series Shape Data. Proc. of Medical Image Computing and Computer Assisted Intervention (MICCAI '11). September 2011.