2013 Winter Project Week:WMHseg

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WMH

Key Investigators

  • Adrian Dalca, Ramesh Sridharan, Polina Golland, MIT
  • Natalia Rost, Jonathan Rosand, MGH

Project Description

Objective

We are developing methods for segmentation of white matter hyperintensity in FLAIR images of stroke patients. The particular challenge here is the specific localization of "useful" WMH in images that are otherwise lower resolution (1mm x 1mm x 7mm) and with cropped fields of view.

Approach, Plan

  • Find and apply appropriate registration method to register cropped, low resolution T1 scans
  • Register T1 scans to FLAIR images with rigid registration
  • Create mask of relevant areas for WMH segmentation from manual segmentations
  • Investigate several known methods for segmentation of WMH segmentation using training images.
  • Write thorough pipline for above steps.

Progress