Difference between revisions of "2014 Summer Project Week:Stroke-ImagingGenetics"

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Image:PW-MIT2014.png|[[2014_Summer_Project_Week#Projects|Projects List]]
 
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Image:WMH_T1.png|Clinical Stroke Image
 
Image:Leuk_model.png|Leukoaraiosis Model
 
Image:Leuk_model.png|Leukoaraiosis Model
 
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==Key Investigators==
 
==Key Investigators==

Revision as of 14:30, 23 June 2014

Home < 2014 Summer Project Week:Stroke-ImagingGenetics


Key Investigators

  • Adrian Dalca, Ramesh Sridharan, Polina Golland, MIT
  • Natalia Rost, Jonathan Rosand, MGH

Project Description

This is one of a series of projects on a large clinical dataset of stroke patients, including T2-FLAIR and DWI imaging. We recently (MICCAI 2014) developed a leukoaraiosis (small vessel disease) probabilistic co-variation model, which we use to differentiate between small vessel disease and acute or chronic stroke on T2-FLAIR.

Average Leukoaraiosis projection

Explore the first component of the model

Objective

  • Here, we wish to investigate the parameters of the model as potential phenotypes against for clinical and genetic analyses.

Approach, Plan

  • We will create the phenotype projections for ~80 stroke patients and experiment with correlating the genetic and clinical factors.

Progress