Difference between revisions of "2016 Summer Project Week/Brain atlas combining histology and MRI"

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==Key Investigators==
 
==Key Investigators==
* Fernando Pérez García
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* Fernando Pérez García ([http://icm-institute.org/en/ Institute of the Brain and Spine], France)
 
   
 
   
 
==Project Description==
 
==Project Description==
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Multimodal 3D visualization is important during the construction of a 3D histology / MRI atlas. Also, the interface must be very intuitive so that the user can easily trace the many contours needed for a precise 3D reconstruction.
  
Description TODO.
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We have chosen 3D Slicer as our development platform because of its flexibility and its huge potential for multimodal 3D visualization. Our goal is to develop an integrated, intuitive extension for manual tracing of contours on stained histological slices that have been coregistered to a high resolution MRI.
  
 
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* Objectives TODO
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* A Slicer Extension to aid in the creation of a 3D histological atlas. Different modules used to:
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** Trace contours
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** Count neurons
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** Visualize the results
 
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* Approach TODO
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* Study the available tools in modules such as "Editor", "Segment Editor" and "Segmentations" so that they can be used in our extension.
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* Create a small preview of the current histological slice (as in [https://www.researchgate.net/profile/Carlos_Ortiz-de-Solorzano/publication/233806662/figure/fig3/AS:299961800511505@1448527874676/Figure-3-Sample-histology-images-corresponding-to-a-lung-lobe-slice-of-a-mouse-17-days.png this image]), so that the user knows where they are in the slice while zooming.
 
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<!-- Progress and Next steps bullet points (fill out at the end of project week) -->
 
<!-- Progress and Next steps bullet points (fill out at the end of project week) -->
 
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Revision as of 14:56, 15 June 2016

Home < 2016 Summer Project Week < Brain atlas combining histology and MRI

Key Investigators

Project Description

Multimodal 3D visualization is important during the construction of a 3D histology / MRI atlas. Also, the interface must be very intuitive so that the user can easily trace the many contours needed for a precise 3D reconstruction.

We have chosen 3D Slicer as our development platform because of its flexibility and its huge potential for multimodal 3D visualization. Our goal is to develop an integrated, intuitive extension for manual tracing of contours on stained histological slices that have been coregistered to a high resolution MRI.

Objective Approach and Plan Progress and Next Steps
  • A Slicer Extension to aid in the creation of a 3D histological atlas. Different modules used to:
    • Trace contours
    • Count neurons
    • Visualize the results
  • Study the available tools in modules such as "Editor", "Segment Editor" and "Segmentations" so that they can be used in our extension.
  • Create a small preview of the current histological slice (as in this image), so that the user knows where they are in the slice while zooming.