Difference between revisions of "2017 Winter Project Week/PkModeling"

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(screenshot for project week 2017)
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==Key Investigators==
 
==Key Investigators==
 
* Andrew Beers, Jayashree Kalpathy-Cramer, MGH
 
* Andrew Beers, Jayashree Kalpathy-Cramer, MGH
 +
* Jim Miller, GE
  
 
==Project Description==
 
==Project Description==

Revision as of 02:54, 11 January 2017

Home < 2017 Winter Project Week < PkModeling

Key Investigators

  • Andrew Beers, Jayashree Kalpathy-Cramer, MGH
  • Jim Miller, GE

Project Description

Objective Approach and Plan Progress and Next Steps
  • PkModeling, a Slicer module meant to derive DCE pharmokinetic parameters via the two and three parameter Tofts model, has not had perfect accuracy on phantoms for the Tofts model. We intend to troubleshoot and address these errors, which we have determined from our previous research to be problems with the implementations of the Tofts model.
  • Make the module more usable and/or intuitive to casual users.
  • Although it may be a larger Slicer infrastructure project, add support to Slicer for 4D Niftis, the main file format of our lab.
  • Debug the module with several test cases and deconstruct the models steps to see where error is introduced to its calculations.
  • Model UI off of successful modules, and seek advice from attendants of Project Week.
  • Probe conversion between MultiVolumes and 4D Nifti files.

Background and References