2017 Winter Project Week/PkModeling

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Home < 2017 Winter Project Week < PkModeling

Key Investigators

  • Andrew Beers, Jayashree Kalpathy-Cramer, MGH

Project Description

Objective Approach and Plan Progress and Next Steps
  • PkModeling, a Slicer module meant to derive DCE pharmokinetic parameters via the two and three parameter Tofts model, has not had perfect accuracy on phantoms for the Tofts model. We intend to troubleshoot and address these errors, which we have determined from our previous research to be problems with the implementations of the Tofts model.
  • Make the module more usable and/or intuitive to casual users.
  • Although it may be a larger Slicer infrastructure project, add support to Slicer for 4D Niftis, the main file format of our lab.
  • Debug the module with several test cases and deconstruct the models steps to see where error is introduced to its calculations.

Background and References