DBP2:MIND:BeyondLesionsProject

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Key Investigators

• H. Jeremy Bockholt
• Mark Scully
• Ross Whitaker
• Steve Pieper
• Vincent Magnotta
• Guido Gerig

Objective

Going beyond classification of crisp boundaries of lesion hyperintensities on FLAIR, how can DTI be incorporated to investigate diffuse lesions. Determine the requirements for potentially looking at white matter intensity abnormalities that may not manifest themselves as "classic lesions" Set up a framework for testing lower FA and higher MD in lupus versus healthy normal volunteers

Approach, Plan

Map out a strategy and timeline with concrete delivers for use of DTI scalars.

Progress