Difference between revisions of "DBP2:MIND:Roadmap"

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(New page: Brain Lesion Analysis in Neuropsychiatric Systemic Lupus Erythematosus Compare Lesion Analysis Tools A number of algorithms for fully or semi-automated lesion analysis will be evalua...)
 
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Brain Lesion Analysis in Neuropsychiatric Systemic Lupus Erythematosus
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=Brain Lesion Analysis in Neuropsychiatric Systemic Lupus Erythematosus=
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==Objective==
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We would like to provide an end-to-end application within the NA-MIC kit to provide individual white matter lesion classification.
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==Roadmap==
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Compare Lesion Analysis Tools
 
Compare Lesion Analysis Tools
 
   
 
   
 
A number of algorithms for fully or semi-automated lesion analysis will be evaluated on brain images from subjects in a study on lupus erythematosis. These include:
 
A number of algorithms for fully or semi-automated lesion analysis will be evaluated on brain images from subjects in a study on lupus erythematosis. These include:
 
   
 
   
1) The tools developed by the UNC group
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1) The tools developed by the UNC group (marcel)
 
   
 
   
2) The tools developed by the BWH group
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2) The tools developed by the BWH group (EM-segment with lesion segmentation)
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3) Tools within Medx (automated lesion classification package)
 
   
 
   
3) Tools within Medx
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4) BRAINS2 (automated lesion classification package)
 
4) BRAINS2
 
 
   
 
   
 
5) manual tracing
 
5) manual tracing
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Incorporation into Slicer
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Incorporation into NA-MIC Kit
 
   
 
   
 
The algorithm with the best performance will be incorporated in Slicer3.
 
The algorithm with the best performance will be incorporated in Slicer3.
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Tutorial
 
Tutorial
 
 
Documentation will be written for a tutorial and sample data sets will be provided
 
Documentation will be written for a tutorial and sample data sets will be provided
 
   
 
   
 
   
 
   
Longitudinal studies
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Hypothesis Testing
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Tools will be developed for comparing differences in lesion number, size, and location with time.
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Performance characterization and validation
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Schedule

Revision as of 15:05, 26 September 2007

Home < DBP2:MIND:Roadmap

Brain Lesion Analysis in Neuropsychiatric Systemic Lupus Erythematosus

Objective

We would like to provide an end-to-end application within the NA-MIC kit to provide individual white matter lesion classification.

Roadmap

Compare Lesion Analysis Tools

A number of algorithms for fully or semi-automated lesion analysis will be evaluated on brain images from subjects in a study on lupus erythematosis. These include:

1) The tools developed by the UNC group (marcel)

2) The tools developed by the BWH group (EM-segment with lesion segmentation)

3) Tools within Medx (automated lesion classification package)

4) BRAINS2 (automated lesion classification package)

5) manual tracing

Data will be collected at both 1.5 and 3T. Data at 1.5T will be obtained with the protocol utilized for current project on lupus at UNM.

Data at 3T will be obtained with sequences optimized for segmentation by the group at Utah.

Comparisons will be based on the approach developed by Martin-Fernandez et al.


Incorporation into NA-MIC Kit

The algorithm with the best performance will be incorporated in Slicer3.


Tutorial Documentation will be written for a tutorial and sample data sets will be provided


Hypothesis Testing


Performance characterization and validation


Schedule