Difference between revisions of "DBP2:UNC:Local Cortical Thickness Pipeline"

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:** Tool: MeshCortThick
 
:** Tool: MeshCortThick
 
:* '''8. Cortical Surface inflation'''
 
:* '''8. Cortical Surface inflation'''
:** Tool: needs to be developped
+
:** Tool: in progress
 
:* '''9. Cortical correspondence on inflated surface'''
 
:* '''9. Cortical correspondence on inflated surface'''
 
:** Tool: UNC Slicer3 external module
 
:** Tool: UNC Slicer3 external module
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:* Genus zero images and surfaces improvement
 
:* Genus zero images and surfaces improvement
:* Cortical surface inflation (reading litterature)
+
:* Cortical surface inflation: module in progress
  
 
=== Future work ===
 
=== Future work ===

Revision as of 20:17, 17 October 2008

Home < DBP2:UNC:Local Cortical Thickness Pipeline

Back to UNC Cortical Thickness Roadmap


Objective

We would like to create an end-to-end application within Slicer3 allowing individual and group analysis of local cortical thickness.

General information

Pipeline description (steps)

Input: T1-weighted image, T2-weighted image, PD-weighted image

  • 1. Tissue segmentation
    • Tool: itkEMS (UNC Slicer3 external module)
  • 2. Atlas-based ROI segmentation: subcortical structures, lateral ventricles, cerebellum
    • 2.1 Deformable registration of T1-weighted pediatric atlas
      • Tool: RegisterImages (Slicer3 module)
    • 2.2. Applying transformations to the structures
      • Tool: ResampleVolume2 (Slicer3 module)
  • 3. White matter map and gray matter map images creation
    • Tool: ImageMath
  • 4. Genus zero images and surfaces creation
    • Tool: GenusZeroImageFilter (UNC Slicer3 external module)
  • 5. Label map creation
    • Tool: ImageMath
  • 6. Laplacian cortical thickness
    • Tool: measureThicknessFilter (UNC Slicer3 external module)
  • 7. Cortical thickness information on genus zero surface
    • Tool: MeshCortThick
  • 8. Cortical Surface inflation
    • Tool: in progress
  • 9. Cortical correspondence on inflated surface
    • Tool: UNC Slicer3 external module

Usage (Command Line)

needs to be done


Analysis on a small pediatric dataset

needs to be done

In progress

  • Genus zero images and surfaces improvement
  • Cortical surface inflation: module in progress

Future work

  • UNC Slicer3 external modules available on NITRIC
  • Workflow for individual analysis (Slicer3 external module using BatchMake)
  • Workflow for group analysis