DBP3:Iowa

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Engineering Action Plan

Morphometric Processing

Goals: Have all the documentation and code in place for BRAINS3 to easily be used by the community.

DTI Processing

Goals: Tools for a longitudinal analysis pipeline of changes measured by fiber tractography to identify white matter tracts that have strong co-morbid degenerative timelines compared to subcortical degeneration over time. Enable the use of the advanced DTI processing in NA-MIC within PREDICT HD. Specifically, adapt all NA-MIC tools to work as individual external Slicer modules (in part they already exist, but need further work), as well as combine them into a single Slicer DTI processing wizard.


Shape Analysis

Goals: Tools for a longitudinal shape analysis pipeline to identify localized changes in basal ganglia tracts that have strong co-morbid degenerative timelines. Enable the use of the advanced SPHARM & particle shape analysis processing in NA-MIC within PREDICT HD.

BatchMake Processing and Grid Wizard

Goals: Create a distributed batch processing pipeline that pulls data from and reports data to XNAT while distributing jobs across a cluster.

Data

Goals: Share a meaningful, fully anonymized subset of the sMRI, fMRI, and DWI Huntington's data.


Outreach

Goals: Inform community of the existence of tools and data sets as well as train them on their use.

Who

  • DBP: Hans Johnson, DBP engineer Mark Scully
  • Algo: Martin Styner, DBP engineer Clement Vachet
  • Eng: Dan Marcus, Jeff Grethe, Marco Ruiz