DBP3:Utah:RegCases

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Background

  • The CARMA Center uses late gadolinium enhanced MRI (LGE-MRI) images to evaluate new patients, predict procedural success, and evaluate therapeutic outcomes. The MRI images for each patient are further accompanied by MR angiographic images (MRA) and manual segmentations of relevant structures. These images are acquired longitudinally over the course of a patient's evaluation, treatment, and follow-up (i.e. months or years). Registration is often necessary to compare images from different time points in a patient's treatment, across patient cohorts at the same stage of disease progression or treatment, or different image types.
Pre-ablation LGE-MRI Image Post-ablation LGE-MRI Image Segmentation of LGE-MRI Image
Carma ex pre.png
Carma ex post.png
Carma ex pre seg.png
MRA Image Immediately Post-ablation (IPA) LGE-MRI Image
Carma ex mra.png
Carma no reflow.png

Registration Case Types

Pre to Post LGE-MRI

Pre to Pre LGE-MRI

Post to Post LGE-MRI

MRA to LGE-MRI

MRA to MRA

Immediately-Post to Post LGE-MRI

CT to LGE-MRI

Vector-Valued Registration

Implementation

  • We need to define a suitable set of registration parameters for each of the above cases
  • We will develop a Slicer extension module with the pre-defined registration parameters for each of the above scenarios