EM Segment

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Key Investigators

  • Sylvain Jaume, MIT
  • Nicolas Rannou, BWH
  • Koen Van Leemput, MGH
  • Polina Golland, MIT
  • Steve Pieper, BWH
  • Ron Kikinis, BWH

Objective

The goal of this project is to create a segmentation module in Slicer3 that offers a high productivity and reliability to the clinician. The primary application is the segmentation of MRI images using a probabilistic atlas.

Approach, Plan

Our algorithm builds upon the Expectation Maximization theory and is structured to let the clinician make the most efficient use of his/her anatomical knowledge. Because of our intuitive visualization of probabilities, the user can understand the probabilistic features of his/her data and can efficiently tune the parameters to obtain the most accurate segmentation. To meet the time constraints of the tasks in a hospital, a main focus has been devoted to the acceleration of the EM segmentation algorithm.

Progress

A Slicer3 module for MRI Bias Field Correction has been developed to serve as a pre-processing step for the EM segmentation and is currently tested by collaborators who study alcohol and stress interaction in primates.

Collaboration