View source for Events:Computational Methods for Radiation Oncology

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==Summary==

[[Image:2011_May_UNC_NA-MIC_Radonc_Meeting.jpg|800px]]

25 researchers attended this meeting from UNC, BWH, MGH, Harvard, and U Michigan.  Several collaboration ideas have emerged and have been enumerated below.

==Date and Location==
Date: Thursday, May 5, 2011

Location: Surgery Education Office, Room CA-034, Carrie Hall, 15 Francis Street.  ([[Media:Directions to CA-034 Carrie Hall 15 Francis Street Boston.doc|Directions]])

In addition, the following information is useful for first time visitors to the hospital:
*http://www.brighamandwomens.org/about_bwh/locations/directions/default.aspx
*On the "Pike map" PDF link (bottom of page), the Carrie Hall building is closest to the 15 Francis St entrance -- enter through the columns.
*On Google Street View/Map, the Carrie Hall building is near the label "Howard Hughes Medical Institute". 

==Agenda==

To brainstorm computational methods for radiation oncology between UNC, NA-MIC, BWH.


*8am: Breakfast
*8:30-10:30am: UNC -presentations about capabilities of current projects, short term and longer term plans 
**'''Julian Rosenman''' 		PLUNC							18 minutes
**'''Gregg Tracton''' 		Software for PLUNC, segmentation, registration  	10 minutes
**'''Stephen Pizer'''			Registration by regression (2 methods), Segmentation via posterior optimization, training probability distributions on s reps and quantile functions, segmentation via correspondence-preserving warps, ant aliasing	23 minutes
**'''Sha Chang'''			Nanotube imaging, incl. for IGRT			10 minutes									
**'''Brandon Frederick''' 		Iterative tomographic reconstruction, CTs at treatment time, gpu’s		15 minutes
**'''Derek Merck'''			3D visualization via model-guided rendering, 3D visualization in PLUNC for RTP			15 minutes			
**'''Ilknur Kabul''' 			Texturing of surfaces, onion skins, and cut planes; interpolation of textures				10 minutes
**'''Hina Shah'''			Registration of endoscopic cine and CT of throat,fused displays of these two registered sources		8 minutes
**'''Ron Alterovitz'''		Planning for brachytherapy with curved needles, FEM software						12 minutes
*10:30 am: Break 
*11:50am-2:30pm NA-MIC/Harvard presentations about capabilities of current projects, short term and longer term plans
**AMIGO (Tina Kapur) (5 minutes)
**Slicer3 to Slicer 4, Radiation Therapy support today, and plans for the next year [[media:Pieper-CMRO-2011-05-05.ppt|(slides)]] ('''Steve Pieper''') (30 minutes)
**SPARKit, Canadian grant for providing open source software platform for radiotherapy, potentially based on NA-MIC Kit [[Media:SparKitIntroBostonRadOnc2011.pdf|(slides)]] ('''Andras Lasso''') (10minutes)
**Head and Neck Cancer NA-MIC DBP ([[Media:2011-CMRO-Sharp.pdf|slides]]) ('''Greg Sharp''') (15 minutes)
**Gynecologic Cancer Brachytherapy Plans ('''Tina Kapur''') (10 minutes)
**Shadie, shading language for volume visualization [[media:Shadie-BW-2011.pdf|(slides)]] ('''Hanspeter Pfister, Milos Hasan, George Chen, John Wolfgang''') (20 minutes)
*Continue presentations...
*2:30pm: Intro of afternoon objectives ('''Julian Rosenman''') 
*2:45pm: What UNC/Boston system combinations ought to be developed -- the Boston perspective ('''Tina Kapur''')
*3pm: What Boston/UNC system combinations ought to be developed -- the UNC perspective ('''Steve Pizer''')
*3:30pm: Comments from Kitware about their capabilities relevant to proposed combinations ('''Brad Davis''')
*4-5pm
** Break and subgroup formation (e.g., merging surgical and radiation treatment planning system; 3D visualization software for treatment planning; image analysis software for treatment planning)
** Subgroups sketch out mechanics for collaborations (http://grants.nih.gov/grants/guide/pa-files/PAR-11-028.html?)
**Summary: what we do next?

==Participants==

#Julian Rosenman, Radiation Oncology, UNC		
#Gregg Tracton, Radiation Physics UNC
#Stephen Pizer, CS and Rad Onc UNC			
#Sha Chang, Radiation Physics UNC												
#Brandon Frederick, UNC
#Derek Merck, UNC					
#Ilknur Kabul 		UNC	
#Hina Shah			UNC
#Ron Alterovitz	 UNC
#Ron Kikinis BWH
#Clare Tempany BWH
#Ferenc Jolesz BWH
#Sandy Wells	BWH
#Steve Pieper Isomics
#Andras Lasso Queens
#Greg Sharp MGH
#Tina Kapur BWH
#Hanspeter Pfister Harvard
#George Chen MGH
#Petter Risholm BWH
#Andrey Fedorov BWH
#James Balter U Michigan
#Brad Davis Kitware
#Andinet Enquobahrie Kitware
#Firdaus Janoos BWH

==Potential Areas of Collaboration==

#Multimodal registrations from BWH with PLUNC
#ITK needs GPU codes
#How to put UNC code into the open source world (from BWH experience)
#Visual bookmarks as cf. Slicer (scene views)
#Tolerance and other surface color washes on textured objects
#Endoscopy and 3D MR segmentation: cervix
#AMIGO w/ endoscopy
#AMIGO w/ curved needles
#Curved needles for biopsies
#Optical CT inclusion
#FEM modeling sharings between BWH and UNC
#Robotics and device tracking sharing: BWH has device tracking expertise: OPENIGT
#Shadie/MGRView or 3D PLUNC or 3D Slicer integration
#Adding cmake/software process to PLUNC
#Problem: how to integrate object-based coordinate systems into object models and integrate UI controls within those coordinate systems?
#MGRView w/ ray-cast volume rendering a la volview/vtk
#Inclusion of Ontario ARKit/SparKit? (adaptive RT)
#What can be taken from PLUNC into Slicer right away?
#There needs to be a remodeling of PLUNC licensing to meet the Slicer sharing philosophy
#US-to-MR or -CT registration brought to RT
#Visualize uncertainty by painting over texture (Pfister/UNC)
#Combine Shadie language with MGRView/PLUNC 3Dview capabilities
#Image analysis and visualization via Slicer (selected modules in use) into PLUNC into MOSAIQ, etc.
#PLUNC Need: Flexibility/refactor?. Multimodal registration. Including context; annotations
#Is there a role for python, numpy?
#Note: WashU CERR has a simple dose engine.  Do we integrate that?
#2d-3d Registration for IGRT using Nanotube Stationary Tomosynthesis  from Siemens, Xinray
#Head and Neck Segmentation by registration and refinement
#Antialiasing algorithm
##How will antialiasing impact DVHs? What is the drift in the dose distribution
##Morphomics Segmentation software for Prostate and Cervix maybe
#James balter collaboration  LA problem
#ITK should have GPU support
#Potential tools from UNC:
##Antialiasing software (potential project week project -- steve pizer, brad davis, petter risholm, andriy fedorov)
##Iterative reconstruction software is shareable
##General GPU tools
##Manual Editing of alignment
##Dose accumulation calculation
#Mechanisms
##Software maintenance R01
##BRP collaborative grant
#Registration of endoscopic images with CT for IGRT: Gyn colposcopy
#Steerable needle planning for gyne brachytherapy 
#How to close the loop with feedback for needle insertion and steering for prostate brachy?
#Open FEM standard for RT
#Slicer License for UNC review: http://www.slicer.org/pages/LicenseText
#http://wiki.na-mic.org/Wiki/index.php/2011_Summer_Project_Week