Difference between revisions of "Exploring multi-modal registration for improved longitudinal modeling of patient-specific 4D DTI data"

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<h3>Objective</h3>
 
<h3>Objective</h3>
* Co-register patient-specific structural and DTI data together with lesion segmentations. Registration is performed in a longitudinal fashion to establish correspondence between the acute and chronic scans from a patient across multiple modalities.
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* Utilize the lesion segmentation framework previously developed by Wang et al. for an improved modeling of longitudinal changes in white matter properties of tracts for a TBI subject.
* Utilize information from the lesion segmentations to guide the tractography and assess white matter changes in and around the lesions sites.  
 
 
 
 
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<h3>Approach, Plan</h3>
 
<h3>Approach, Plan</h3>
 
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* Co-register patient-specific structural and DTI data, together with lesion segmentations. Registration is performed using Slicer in a longitudinal fashion to establish correspondence between the acute and chronic scans from a patient across multiple modalities.
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* Utilize information from the lesion segmentations to guide the tractography.
 +
* Assess white matter changes longitudinally in tracts close to the lesions sites.
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Revision as of 15:13, 17 June 2013

Home < Exploring multi-modal registration for improved longitudinal modeling of patient-specific 4D DTI data

Key Investigators

  • Utah: Anuja Sharma, Bo Wang, Guido Gerig
  • UCLA: Andrei Irimia, Micah Chambers, Jack Van Horn


Objective

  • Utilize the lesion segmentation framework previously developed by Wang et al. for an improved modeling of longitudinal changes in white matter properties of tracts for a TBI subject.

Approach, Plan

  • Co-register patient-specific structural and DTI data, together with lesion segmentations. Registration is performed using Slicer in a longitudinal fashion to establish correspondence between the acute and chronic scans from a patient across multiple modalities.
  • Utilize information from the lesion segmentations to guide the tractography.
  • Assess white matter changes longitudinally in tracts close to the lesions sites.


Progress


References