Difference between revisions of "ITK Spherical Harmonics filter for shape analysis of cell nuclei"

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(Undo revision 54067 by Rmachiraju (Talk))
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==Key Investigators==
 
==Key Investigators==
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* OSU: Liya Ding, Kun Huang, Raghu Machiraju
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* OSU: Shantanu Singh, Raghu Machiraju
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* Harvard Medical School: Sean Megason
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* Harvard Medical School: Arnaud Gelas, Sean Megason
  
 
==Project==
 
==Project==
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<h3>Objective</h3>
 
<h3>Objective</h3>
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3D histology stacks are being increasingly used to understand gross anatomical changes and to provide
 
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valuable educational contexts. Most existing toolkits allow a 2D approach and do not meet the challenges
 
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posed by 3D histology. ITKv4 can facilitate the realization application level toolkits that will allow for a
 
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sensible registration, segmentation and reconstruction of digital slides depicting various organs and tissue
 
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systems. Modules will be included that will allow for pre-processing (color correction, artifact removal,
 
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etc.), rigid and non-rigid registration, material-based segmentation, and visualization.
 
  
 
</div>
 
</div>
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<h3>Approach, Plan</h3>
 
<h3>Approach, Plan</h3>
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we have developed a series of algorithms and
 
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computational pipelines for processing large microscopy images using heterogeneous
 
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computing platforms including GPU and CPU/GPU clusters. We will extend ITKv4 by
 
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incorporating algorithm families that will allow for comprehensive processing of light
 
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microscopy images to enable both 2D and 3D digital histology.
 
  
 
</div>
 
</div>
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<h3>Progress</h3>
 
<h3>Progress</h3>
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We are creating three different workflows to achieve our goals. These
 
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workflows accomplish (i) pre-preprocessing the data, (ii) registration/3D reconstruction
 
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and segmentation/classification of tissue regions from multi-channel data, (iii) and the
 
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visualization of the microstructure.
 
  
 
</div>
 
</div>

Revision as of 14:03, 16 June 2010

Home < ITK Spherical Harmonics filter for shape analysis of cell nuclei

Key Investigators

  • OSU: Shantanu Singh, Raghu Machiraju
  • Harvard Medical School: Arnaud Gelas, Sean Megason

Project

Objective

Approach, Plan

Progress

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