Difference between revisions of "Linear Mixed-effects shape model to explore Huntington's Disease Data"

From NAMIC Wiki
Jump to: navigation, search
Line 8: Line 8:
 
==Key Investigators==
 
==Key Investigators==
 
* UIowa: Hans Johnson, Dave Welch
 
* UIowa: Hans Johnson, Dave Welch
* Utah: Manasi Datar, Ross Whitaker
+
* Utah: Manasi Datar, Josh Cates, Ross Whitaker
  
 
<div style="margin: 20px;">
 
<div style="margin: 20px;">
Line 34: Line 34:
 
* ITKv4 module for mixed-effects model (Josh) available for Manasi to test
 
* ITKv4 module for mixed-effects model (Josh) available for Manasi to test
 
** ITKv4 module tested on Linux system
 
** ITKv4 module tested on Linux system
** Mixed-effects model for single component HD shapes (in progress)
+
** Mixed-effects model for shapes from a single structure from the HD data (in progress)
 
* Once tested, this module can be used by UIowa team on a larger cohort of cases
 
* Once tested, this module can be used by UIowa team on a larger cohort of cases
  

Revision as of 13:54, 20 June 2013

Home < Linear Mixed-effects shape model to explore Huntington's Disease Data

Key Investigators

  • UIowa: Hans Johnson, Dave Welch
  • Utah: Manasi Datar, Josh Cates, Ross Whitaker

Objective

Make the linear mixed-effects shape model accessible for further exploration of Huntington's Disease Data

Approach, Plan

Meet with UIowa team to:

  • give an overview of results from the linear mixed-effects shape model
  • explain the ShapeWorks command line tools to optimze and analyze correspondences
  • discuss next steps toward making these tools accessible to UIowa team, to facilitate further exploration of the Huntington's disease Data

Progress

  • preliminary results look promising
  • ITKv4 module for mixed-effects model (Josh) available for Manasi to test
    • ITKv4 module tested on Linux system
    • Mixed-effects model for shapes from a single structure from the HD data (in progress)
  • Once tested, this module can be used by UIowa team on a larger cohort of cases


References

M Datar, P Muralidharan, A Kumar, S Gouttard, J Piven, G Gerig, RT Whitaker, PT Fletcher, Mixed-Effects Shape Models for Estimating Longitudinal Changes in Anatomy, STIA 2012