Revision as of 15:54, 20 July 2009

Home < MeningiomaMRIRegistrationStudy

Objective

Accurate registration of same patient/same modality MRI data for longitudinal analysis of tumor progression.

Compare the accuracy of registration using existing Slicer and non-Slicer tools
Identify parameter settings that produce satisfactory results
Outline the limitations of the available registration tools in the context of the specific clinical research application

Input images: isotropic post-contrast T1 MRI acquired at different locations of BWH during 2006-2008, used under medical records study IRB. Time period between acquisition of scans for each patient is about 1 year.
Ground truth transformation: not available
Expert landmarks for registration evaluation: not available
Checkerboard appearance of unregistered images for the representative data of interest

qualitative assessment: visually pleasing results
quantitative assessment: something better than "visually pleasing" (TBD)
minimum execution time to meet the application requirements: interactive quantification of tumor growth

flirt -in ${TIME_POINT_2} -ref ${TIME_POINT_1} -omat ${FLIRT_TRANSFORM} -out ${RESAMPLED_IMAGE} -dof 6 -v

@@ Line 61: / Line 61: @@
 ===FSL FLIRT===
+* [http://www.fmrib.ox.ac.uk/fsl/flirt/index.html FSL FLIRT]
+* [http://www.fmrib.ox.ac.uk/analysis/research/flirt/ Technical details]
+* parameters:
+<pre>
+flirt -in ${TIME_POINT_2} -ref ${TIME_POINT_1} -omat ${FLIRT_TRANSFORM} -out ${RESAMPLED_IMAGE} -dof 6 -v
+</pre>
+* execution time: ~4 min
 ==Parameter exploration==