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Core 1: Algorithms
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Back to [[NA-MIC_Collaborations|NA-MIC_Collaborations]]
  
* Eric Grimson: [http://crisp.cit.nih.gov/crisp/CRISP_LIB.getdoc?textkey=7015019&p_grant_num=5R01NS051826-02&p_query=&ticket=23536649&p_audit_session_id=114807056&p_keywords= 5R01NS051826-02 Computational Modeling of Anatomical Shape Distributions]
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'''Objective:''' To quantify changes in diffusion properties along the cingulum bundle for schizophrenics and normal controls.
* David Kennedy: [http://crisp.cit.nih.gov/crisp/CRISP_LIB.getdoc?textkey=7056141&p_grant_num=5K12MH069281-03&p_query=&ticket=23536693&p_audit_session_id=114807056&p_keywords= 5K12MH069281-03 Neuroimaging Neuroinformatics Training Program], [http://crisp.cit.nih.gov/crisp/CRISP_LIB.getdoc?textkey=6941591&p_grant_num=5R01NS034189-11&p_query=&ticket=23536693&p_audit_session_id=114807056&p_keywords= 5R01NS034189-11 Anatomic Morphologic Analysis of MR Brain Images]
 
* Allen Tannenbaum:
 
* Guido Gerig: [http://crisp.cit.nih.gov/crisp/CRISP_LIB.getdoc?textkey=6690190&p_grant_num=1P50MH064065-01A19002&p_query=&ticket=25176558&p_audit_session_id=165467414&p_keywords= 1P50MH064065-01A19002 Core--Neuroimaging and morphology],
 
  
[http://crisp.cit.nih.gov/crisp/CRISP_LIB.getdoc?textkey=6613380&p_grant_num=2P01CA047982-12A10005&p_query=(Neuroimaging)&ticket=25176624&p_audit_session_id=165467414&p_audit_score=32&p_audit_numfound=1&p_keywords=Neuroimaging 2P01CA047982-12A10005 Shape of Subcortical Brain Structures in Schizophrenia], [http://crisp.cit.nih.gov/crisp/CRISP_LIB.getdoc?textkey=6988774&p_grant_num=1U54EB005149-010004&p_query=(Neuroimaging)&ticket=25176647&p_audit_session_id=165467414&p_audit_score=21&p_audit_numfound=1&p_keywords=Neuroimaging 1U54EB005149-010004 STRUCTURAL ANALYSIS OF ANATOMICAL SHAPES AND OF WHITE MATTER TRACTS], [http://crisp.cit.nih.gov/crisp/CRISP_LIB.getdoc?textkey=6613382&p_grant_num=2P01CA047982-12A19003&p_query=(imaging)&ticket=25176711&p_audit_session_id=165467414&p_audit_score=7&p_audit_numfound=1&p_keywords=imaging 2P01CA047982-12A19003 Core--Validation Methodology]
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'''Progress:''' We improved the diffusion MRI module in slicer to allow for a better fiber selection (based on multiple regions of interest) as well as fiber clustering. We set up a processing pipeline to allow for statistical computations of fiber diffusion properties across the fibers of a fiber bundle and along the bundle itself. Further, we are in the process of developing a continuous representation of fiber bundles (see Figure) to allow for a more geometric computation of bundle diffusion quantities.
  
* Ross Whitaker:
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'''Key Investigators:'''
  
Core 3: DBP
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* Harvard PNL: Marc Niethammer, Sylvain Bouix, Marek Kubicki, Mark Dreusicke, Martha Shenton
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* MIT: CF Westin, Lauren O'Donnell, Raul San Jose
  
* Martha Shenton: [http://crisp.cit.nih.gov/crisp/CRISP_LIB.getdoc?textkey=7141113&p_grant_num=7K05MH070047-03&p_query=&ticket=23604627&p_audit_session_id=115583617&p_keywords= 7K05MH070047-03 Clinical Symptons & Brain Abnormalities in Schizophrenia], [http://crisp.cit.nih.gov/crisp/CRISP_LIB.getdoc?textkey=7115712&p_grant_num=5R01MH050740-12&p_query=&ticket=23604627&p_audit_session_id=115583617&p_keywords= 5R01MH050740-12 Computerized Image Analyses of MR Scans in Schizophrenia]
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'''Links:'''
* Andy Saykin: [http://crisp.cit.nih.gov/crisp/CRISP_LIB.getdoc?textkey=6934525&p_grant_num=5R01AG019771-05&p_query=&ticket=23604676&p_audit_session_id=115583617&p_keywords= 5R01AG019771-05 Memory Circuitry in MCI and Early Alzheimer's Disease], [http://crisp.cit.nih.gov/crisp/CRISP_LIB.getdoc?textkey=7106608&p_grant_num=5R01CA101318-04&p_query=&ticket=23604676&p_audit_session_id=115583617&p_keywords= 5R01CA101318-04 Neural Mechanisms of Chemotherapy-Induced Cognitive Dis]
 
* Steven Potkin: [http://crisp.cit.nih.gov/crisp/CRISP_LIB.getdoc?textkey=7107205&p_grant_num=5P20RR020837-03&p_query=&ticket=23605260&p_audit_session_id=115583617&p_keywords= 5P20RR020837-03 Transdisciplinary Imaging Genetics Center (1 of 2)(RMI)], [http://crisp.cit.nih.gov/crisp/CRISP_LIB.getdoc?textkey=7088050&p_grant_num=1U24RR021992-01A1&p_query=&ticket=23605260&p_audit_session_id=115583617&p_keywords= 1U24RR021992-01A1 Function BIRN]
 
* Jim Kenndy: [http://crisp.cit.nih.gov/crisp/CRISP_LIB.getdoc?textkey=7253142&p_grant_num=5P01MH056193-100001&p_query=&ticket=23605262&p_audit_session_id=115583617&p_keywords= 5P01MH056193-100001 Genetics of childhood onset depression: relation to psychophysiologic measures]
 
  
=== Compiled for Mike Ackermann on 17:13, 13 September 2006 (EDT) ===
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* [[DBP:Harvard:Collaboration:MITDTI|DBP:Harvard:Collaboration:MITDTI]]
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* http://pnl.bwh.harvard.edu/index.html
  
* NCBC NA-MIC
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'''Representative Image and Descriptive Caption:'''
* DBP Title: STRUCTURAL AND FUNCTIONAL CONNECTIVITY IN SCHIZOPHRENIA
 
* PI: Martha Shenton
 
* Grant #:5K05MH070047-04
 
* HSA:
 
* funding ends: 31-AUG-2009
 
  
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<div class="thumb tleft"><div style="width: 402px">[[Image:Cingulum_reseeded_withtrajectories.png|[[Image:400px-Cingulum_reseeded_withtrajectories.png|Cingulum bundle with arclength parameterization.]]]]<div class="thumbcaption"><div class="magnify" style="float: right">[[Image:Cingulum_reseeded_withtrajectories.png|[[Image:magnify-clip.png|Enlarge]]]]</div>Cingulum bundle with arclength parameterization.</div></div></div>
 
 
* NCBC NA-MIC
 
* DBP Title: STRUCTURAL AND FUNCTIONAL CONNECTIVITY IN SCHIZOPHRENIA
 
* PI: Martha Shenton
 
* Grant #:5R01MH050740-12
 
* HSA*: Douglas Meinecke
 
* funding ends: 30-JUN-2010
 
 
 
----
 
 
 
* NCBC NA-MIC
 
* DBP Title: STRUCTURAL AND FUNCTIONAL CONNECTIVITY IN SCHIZOPHRENIA
 
* PI: Andrew Saykin
 
* Grant #:5R01AG019771-05
 
* HSA*:
 
* funding ends: 31-AUG-2007
 
 
 
----
 
 
 
* NCBC NA-MIC
 
* DBP Title: STRUCTURAL AND FUNCTIONAL CONNECTIVITY IN SCHIZOPHRENIA
 
* PI: Andrew Saykin
 
* Grant #:5R01CA101318-04
 
* HSA*:
 
* funding ends: 31-MAY-2008
 
 
 
----
 
 
 
* NCBC NA-MIC
 
* DBP Title: TRANSDISCIPLINARY IMAGING GENETICS CENTER
 
* PI: Steven Potkin
 
* Grant #: 5P20RR020837-03
 
* HSA*: Greg Farber
 
* funding ends: 31-JUL-2007
 
 
 
----
 
 
 
* NCBC NA-MIC
 
* DBP Title: FUNCTIONAL IMAGING BIOINFORMATICS RESEARCH NETWORK (FBIRN)
 
* PI: Steven Potkin
 
* Grant #: 1U24RR021992-01A1
 
* HSA*: Greg Farber
 
* funding ends: 30-NOV-2010
 
 
 
----
 
 
 
* NCBC NA-MIC
 
* DBP Title: FUNCTIONAL IMAGING AND GENETICS IN SCHIZOPHRENIA:THE SEARCH FOR ENDOPHENOTYPES
 
* PI: James Kennedy
 
* Grant #: 5P01MH056193-100001
 
* HSA*: Rajeev Chandok
 
* funding ends:June 30, 2007.
 

Revision as of 14:03, 18 December 2006

Home < NA
Back to NA-MIC_Collaborations

Objective: To quantify changes in diffusion properties along the cingulum bundle for schizophrenics and normal controls.

Progress: We improved the diffusion MRI module in slicer to allow for a better fiber selection (based on multiple regions of interest) as well as fiber clustering. We set up a processing pipeline to allow for statistical computations of fiber diffusion properties across the fibers of a fiber bundle and along the bundle itself. Further, we are in the process of developing a continuous representation of fiber bundles (see Figure) to allow for a more geometric computation of bundle diffusion quantities.

Key Investigators:

  • Harvard PNL: Marc Niethammer, Sylvain Bouix, Marek Kubicki, Mark Dreusicke, Martha Shenton
  • MIT: CF Westin, Lauren O'Donnell, Raul San Jose

Links:

Representative Image and Descriptive Caption:

Cingulum bundle with arclength parameterization.
Enlarge
Cingulum bundle with arclength parameterization.