NA-MIC/Projects/External Collaboration/W&M CRTC

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Key Investigators

• Nikos Chrisochoides, CRTC (Project lead)
• Andrey Fedorov, CRTC
• Luis Ibanez, Kitware
• Jim Miller, Kitware
• Dan Marcus
• Tina Kapur

Objective

The mission of the Center for Real-Time Computing is to promote innovation in time critical applications like medical image analysis for Image Guided Therapy. The application of our focus is non-rigid image registration (NRR) for image-guided neurosurgery. The objective is to improve the performance, accuracy and usability of the existing method. There are two sub-projects we plan to explore.

1. Distributed parametric search for optimum parameter setting during NRR. This project includes three components: 1) development/evaluation of tools and methods for automated registration validation; 2) collection of ground truth data sets; 3) development of the high performance computing infrastructure.

2. Tetrahedral mesh generation for intra-cranial cavity discretization used in physics-based NRR.

Approach, Plan

1. Distributed parametric search:

1. discuss available tools and methods for automated validation
2. 75+ tumor resection dataset -- would like to be able to use it
3. evaluate the infrastructure options: GWE/GSlicer3? web portal? TeraGrid?
4. collect feedback from potential users

2. Tetrahedral mesh generation:

1. meshing TCON Thu 3:00-3:30pm
2. status of unstructured mesh visualization in Slicer3
3. meshing as a plugin in Slicer3

Progress

Funding

This work is supported in part by NSF grant CSI-719929 and by John Simon Guggenheim Memorial Foundation.

References

• CRTC web site: