Difference between revisions of "ProjectWeek200706:CorticalThicknessForAutism"

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===Key Investigators===
 
===Key Investigators===
* UNC: Clement Vachet
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* UNC: Heather Cody Hazlett, Martin Styner, Clement Vachet
* MGH: ?
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* MGH: Lilla Zollei
 
 
 
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<h1>Objective</h1>
 
<h1>Objective</h1>
Our goal is to measure cortical thickness evolution at two cross-sectional time periods (2 years with follow-up at 4 years) comparing autistic children and controls, which include typical development and developmental delays. We want to be able to make statistical group comparison considering an average cortical thickness map.
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Our goal is to begin a longitudinal study of early brain development by cortical thickness in autistic children and controls (2 years with follow-up at 4 years). We want to be able to make statistical group comparisons.  
  
  
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<h1>Approach, Plan</h1>
 
<h1>Approach, Plan</h1>
  
Our approach is to run FreeSurfer software on several cases. The main challenge we expect is to
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Our approach is to locally compute the cortical thickness and establish local cortical correspondence in order to compare our populations.
 
 
Our plan for the project week is to learn on use of FreeSurfer, and use our developped itkEMS tool, to
 
  
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Our plan is to learn how to use FreeSurfer in a pediatric age group, and run it on several cases.
 +
We would also like to use our itkEMS Tissue Segmentation tool to incorporate its results in the FreeSurfer pipeline.
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Moreover a study comparison between our CortThick tool and Freesurfer needs to be done to compare methods' reliabilities.
  
 
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<h1>Progress</h1>
 
<h1>Progress</h1>
  
This section will get filled out at the end of the Project week.
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* Jeremy Bockholt helped Clement with how to set up freesurfer autorecon processes.
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* Several pediatric cases are running on the UNC system using FreeSurfer
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Latest revision as of 15:38, 4 December 2007

Home < ProjectWeek200706:CorticalThicknessForAutism


Key Investigators

  • UNC: Heather Cody Hazlett, Martin Styner, Clement Vachet
  • MGH: Lilla Zollei

Objective

Our goal is to begin a longitudinal study of early brain development by cortical thickness in autistic children and controls (2 years with follow-up at 4 years). We want to be able to make statistical group comparisons.


Approach, Plan

Our approach is to locally compute the cortical thickness and establish local cortical correspondence in order to compare our populations.

Our plan is to learn how to use FreeSurfer in a pediatric age group, and run it on several cases. We would also like to use our itkEMS Tissue Segmentation tool to incorporate its results in the FreeSurfer pipeline. Moreover a study comparison between our CortThick tool and Freesurfer needs to be done to compare methods' reliabilities.

Progress

  • Jeremy Bockholt helped Clement with how to set up freesurfer autorecon processes.
  • Several pediatric cases are running on the UNC system using FreeSurfer




References

Additional Information