Difference between revisions of "ProjectWeek200706:CorticalThicknessForAutism"

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===Key Investigators===
 
===Key Investigators===
 
* UNC: Heather Cody Hazlett, Martin Styner, Clement Vachet
 
* UNC: Heather Cody Hazlett, Martin Styner, Clement Vachet
* MGH: ?
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* MGH: Lilla Zollei
 
 
 
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<h1>Objective</h1>
 
<h1>Objective</h1>
Our goal is to begin a longitudinal study of early brain development considering autistic children and controls (2 years with follow-up at 4 years). We want to be able to make statistical group comparisons.  
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Our goal is to begin a longitudinal study of early brain development by cortical thickness in autistic children and controls (2 years with follow-up at 4 years). We want to be able to make statistical group comparisons.  
  
  
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<h1>Approach, Plan</h1>
 
<h1>Approach, Plan</h1>
  
Our approach is to create an average cortical thickness map for each population.
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Our approach is to locally compute the cortical thickness and establish local cortical correspondence in order to compare our populations.
  
Our plan for the project week is to learn how to use FreeSurfer, and run it on several cases.  
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Our plan is to learn how to use FreeSurfer in a pediatric age group, and run it on several cases.  
We would also like to use our itkEMS lab tool to compute cortical thickness on segmented images.
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We would also like to use our itkEMS Tissue Segmentation tool to incorporate its results in the FreeSurfer pipeline.
A study comparison between our CortThick tool and Freesurfer needs to be done to study reliability of the process.
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Moreover a study comparison between our CortThick tool and Freesurfer needs to be done to compare methods' reliabilities.
  
 
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<h1>Progress</h1>
 
<h1>Progress</h1>
  
This section will get filled out at the end of the Project week.
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* Jeremy Bockholt helped Clement with how to set up freesurfer autorecon processes.
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* Several pediatric cases are running on the UNC system using FreeSurfer
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Latest revision as of 15:38, 4 December 2007

Home < ProjectWeek200706:CorticalThicknessForAutism


Key Investigators

  • UNC: Heather Cody Hazlett, Martin Styner, Clement Vachet
  • MGH: Lilla Zollei

Objective

Our goal is to begin a longitudinal study of early brain development by cortical thickness in autistic children and controls (2 years with follow-up at 4 years). We want to be able to make statistical group comparisons.


Approach, Plan

Our approach is to locally compute the cortical thickness and establish local cortical correspondence in order to compare our populations.

Our plan is to learn how to use FreeSurfer in a pediatric age group, and run it on several cases. We would also like to use our itkEMS Tissue Segmentation tool to incorporate its results in the FreeSurfer pipeline. Moreover a study comparison between our CortThick tool and Freesurfer needs to be done to compare methods' reliabilities.

Progress

  • Jeremy Bockholt helped Clement with how to set up freesurfer autorecon processes.
  • Several pediatric cases are running on the UNC system using FreeSurfer




References

Additional Information