Difference between revisions of "Project Week 25/Segmentation for improving image registration of preoperative MRI with intraoperative ultrasound images for neuro-navigation"

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==Background and References==
 
==Background and References==
 
<!-- Use this space for information that may help people better understand your project, like links to papers, source code, or data -->
 
<!-- Use this space for information that may help people better understand your project, like links to papers, source code, or data -->
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In glioma surgery neuronavigation systems assist in determining the tumor's location and estimating its extent.  However, the intraoperative situation diverges seriously from the preoperative situation in the MRI scan
 +
displayed on the navigation system.  The movement of brain tissue during surgery,  i.e.,  caused by brainshift
 +
and tissue removal, must be considered mentally by the surgeon.  A task that gets more challenging in later
 +
phases of the tumor resection.
 +
 +
Besides, it is an exhaustive issue and the shift of cerebral structures must be
 +
expected being non-uniform and that it implies a deformation of the image data.  This makes it especially hard
 +
to mentally predict and model.
 +
 +
Thus,  intraoperative  imaging  modalities  are  used  to  visualize  the  current  intraoperative  situation.  IUS,
 +
for  instance,  is  easy  to  use  intraoperatively,  offers real-time  information,  is  widely  available  at  low  cost  and
 +
causes no radiation.  These are important advantages when iUS is compared with iCT or iMRI. However, in
 +
image-guided surgery precise image registration of iUS and preMRI and the thereon-based image fusion is still
 +
an unsolved problem.  The different representations of cerebral structures in both modalities as well as
 +
artifacts within the iUS, hinder direct fusion of both modalities.

Revision as of 10:55, 23 June 2017

Home < Project Week 25 < Segmentation for improving image registration of preoperative MRI with intraoperative ultrasound images for neuro-navigation

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Key Investigators

Project Description

Objective Approach and Plan Progress and Next Steps
  • Segmented multiple anatomical structures/landmarks in both MRI and Ultrasound (US) images, using machine learning algorithms (applicability of Deep Learning algorithms is currently tested, DL for US-images, data augmentation...).
  • The next step would be to analyze the improvement of registration quality with different segmentations/generated landmarks in order to adapt the segmentation algorithms.
  • Starting from multi-modal image segmentation in preopertive MRI and intraoperative Ultrasound images,

it would be to discuss in which "form" one or multiple segmented structures should influence the registration result.

Illustrations

RegistrationInNeuroNavigationSystem.png

Using segmented structures as guiding frame for multi-modal image registration:

MultimodalImageSegmentation3.png

Background and References

In glioma surgery neuronavigation systems assist in determining the tumor's location and estimating its extent. However, the intraoperative situation diverges seriously from the preoperative situation in the MRI scan displayed on the navigation system. The movement of brain tissue during surgery, i.e., caused by brainshift and tissue removal, must be considered mentally by the surgeon. A task that gets more challenging in later phases of the tumor resection.

Besides, it is an exhaustive issue and the shift of cerebral structures must be expected being non-uniform and that it implies a deformation of the image data. This makes it especially hard to mentally predict and model.

Thus, intraoperative imaging modalities are used to visualize the current intraoperative situation. IUS, for instance, is easy to use intraoperatively, offers real-time information, is widely available at low cost and causes no radiation. These are important advantages when iUS is compared with iCT or iMRI. However, in image-guided surgery precise image registration of iUS and preMRI and the thereon-based image fusion is still an unsolved problem. The different representations of cerebral structures in both modalities as well as artifacts within the iUS, hinder direct fusion of both modalities.