Difference between revisions of "Projects:CorpusCallosumFiberTractography"

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= Corpus Callosum Fiber Tractography =
 
 
 
  Back to [[NA-MIC_Collaborations|NA-MIC_Collaborations]]
 
  Back to [[NA-MIC_Collaborations|NA-MIC_Collaborations]]
  
'''Objectives'''
+
= Corpus Callosum Fiber Tractography =
  
 
Previous studies have observed morphological abnormalities of the corpus callosum in schizophrenia (link to paper below), while other studies have shown abnormal brain activation during memory tasks. The goal of this project is to examine the integrity of fibers in the corpus callosum in patients with schizophrenia and determine whether this is associated with brain activation during memory tasks.
 
Previous studies have observed morphological abnormalities of the corpus callosum in schizophrenia (link to paper below), while other studies have shown abnormal brain activation during memory tasks. The goal of this project is to examine the integrity of fibers in the corpus callosum in patients with schizophrenia and determine whether this is associated with brain activation during memory tasks.
  
'''Progress'''
+
= Description = 
  
 
Fiber tractography method developed and we have begun to apply it to data collected thus far. An example is pictured below. A link to sample DTI data is also below. [[Image:NAMIC_callosum_tracts_prelim.jpg|[[Image:NAMIC_callosum_tracts_prelim.jpg|Image:NAMIC_callosum_tracts_prelim.jpg]]]]
 
Fiber tractography method developed and we have begun to apply it to data collected thus far. An example is pictured below. A link to sample DTI data is also below. [[Image:NAMIC_callosum_tracts_prelim.jpg|[[Image:NAMIC_callosum_tracts_prelim.jpg|Image:NAMIC_callosum_tracts_prelim.jpg]]]]
  
''References''
+
= Key Investigators =
  
'''Key Investigators'''
+
* Dartmouth: John West, Andrew Saykin, Laura Flashman, Paul Wang
  
* Dartmouth: John West, Andrew Saykin, Laura Flashman, Paul Wang
+
= Publications =
 +
 
 +
''In Print''
 +
 
 +
[http://www.na-mic.org/Special:Publications?text=Projects%3ACorpusCallosumFiberTractography&submit=Search&words=all&title=checked&keywords=checked&authors=checked&abstract=checked&sponsors=checked&searchbytag=checked| NA-MIC Publications Database]
  
'''Links'''
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= Links =
  
* Paper, Neurobiology of Aging, in press: [http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T09-4HGM701-3&_user=489293&_handle=V-WA-A-W-AEU-MsSAYZW-UUW-U-AAVEAEAWVU-AAVZDDWUVU-YVUCEAAYD-AEU-U&_fmt=summary&_coverDate=11%2F04%2F2005&_rdoc=95&_orig=browse&_srch=%23toc%234857%239999%23999999999%2399999!&_cdi=4857&view=c&_acct=C000022698&_version=1&_urlVersion=0&_userid=489293&md5=721faeff8b07e7d57550a5c5f921a498 Regionally specific atrophy of the corpus callosum in AD, MCI and cognitive complaints]
 
 
* [[DBP:Marek_Kubicki_visit_Dartmouth_December_20_2005|December 20, 2005: Marek Kubicki visit to Dartmouth]]
 
* [[DBP:Marek_Kubicki_visit_Dartmouth_December_20_2005|December 20, 2005: Marek Kubicki visit to Dartmouth]]
 
* [[DBP:Andy_Saykin_visit_BWH_December_14_2005|December 14, 2005: Andy Saykin and Group visit to Brigham and Women's Hospital]]
 
* [[DBP:Andy_Saykin_visit_BWH_December_14_2005|December 14, 2005: Andy Saykin and Group visit to Brigham and Women's Hospital]]
 
* Sample Data: https://portal.nbirn.net/BIRN/cgi-bin/DataGrid/browse.cgi?browseloc=/home/Projects/NAMIC__0003/Files/Dartmouth/HealthyControls6
 
* Sample Data: https://portal.nbirn.net/BIRN/cgi-bin/DataGrid/browse.cgi?browseloc=/home/Projects/NAMIC__0003/Files/Dartmouth/HealthyControls6

Revision as of 03:34, 27 November 2007

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Corpus Callosum Fiber Tractography

Previous studies have observed morphological abnormalities of the corpus callosum in schizophrenia (link to paper below), while other studies have shown abnormal brain activation during memory tasks. The goal of this project is to examine the integrity of fibers in the corpus callosum in patients with schizophrenia and determine whether this is associated with brain activation during memory tasks.

Description

Fiber tractography method developed and we have begun to apply it to data collected thus far. An example is pictured below. A link to sample DTI data is also below.

Key Investigators

  • Dartmouth: John West, Andrew Saykin, Laura Flashman, Paul Wang

Publications

In Print

NA-MIC Publications Database

Links