# Difference between revisions of "Projects:MultiscaleShapeSegmentation"

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− | Back to [[NA- | + | Back to [[NA-MIC_Internal_Collaborations:StructuralImageAnalysis|NA-MIC Collaborations]], [[Algorithm:Stony Brook|Stony Brook University Algorithms]], [[Algorithm:UNC|UNC Algorithms]], [[Engineering:GE|GE Engineering]], [[Engineering:Kitware|Kitware Engineering]], [[DBP1:Harvard|Harvard DBP 1]] |

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+ | = Multiscale Shape Segmentation = | ||

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To represent multiscale variations in a shape population in order to drive the segmentation of deep brain structures, such as the caudate nucleus or the hippocampus. | To represent multiscale variations in a shape population in order to drive the segmentation of deep brain structures, such as the caudate nucleus or the hippocampus. | ||

− | == | + | = Description = |

+ | |||

+ | == Shape Representation and Prior == | ||

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The overview of our shape representation is given in Figure 1. Our technique defines a multiscale parametric model of surfaces belonging to the same population using a compact set of spherical wavelets targeted to that population (Figure 2). We further refine the shape representation by separating into groups wavelet coefficients that describe independent global and/or local biological variations in the population, using spectral graph partitioning. We then learn a prior probability distribution induced over each group to explicitly encode these variations at different scales and spatial locations (Figure 4) [1]. | The overview of our shape representation is given in Figure 1. Our technique defines a multiscale parametric model of surfaces belonging to the same population using a compact set of spherical wavelets targeted to that population (Figure 2). We further refine the shape representation by separating into groups wavelet coefficients that describe independent global and/or local biological variations in the population, using spectral graph partitioning. We then learn a prior probability distribution induced over each group to explicitly encode these variations at different scales and spatial locations (Figure 4) [1]. | ||

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[[Image:Gatech_SW_mscale_shape.png|thumb|200px|Figure 2: A shape is represented using spherical wavelet coefficients]] | [[Image:Gatech_SW_mscale_shape.png|thumb|200px|Figure 2: A shape is represented using spherical wavelet coefficients]] | ||

− | + | == Segmentation == | |

− | Based on this representation, we derive a parametric active | + | |

+ | Based on this representation, we derive a parametric active surfaceIn evolution using the multiscale prior coefficients as parameters for our optimization procedure to naturally include the prior for segmentation. Additionally, the optimization method can be applied in a coarse-to-fine manner. | ||

+ | |||

+ | == Results == | ||

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We applied our algorithm to the caudate nucleus, a brain structure of interest in the study of schizophrenia [2]. Our validation shows our algorithm is computationally efficient and outperforms the Active Shape Model (ASM) algorithm, by capturing finer shape details. | We applied our algorithm to the caudate nucleus, a brain structure of interest in the study of schizophrenia [2]. Our validation shows our algorithm is computationally efficient and outperforms the Active Shape Model (ASM) algorithm, by capturing finer shape details. | ||

− | + | = Key Investigators = | |

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− | + | * Georgia Tech Algorithms: Delphine Nain, Aaron Bobick, Allen Tannenbaum | |

+ | * UNC Algorithms: Martin Styner | ||

+ | * GE Engineering: Jim Miller | ||

+ | * Kitware Engineering: Luis Ibanez | ||

+ | * Harvard DBP 1: Steven Haker, James Levitt, Marc Niethammer, Sylvain Bouix, Martha Shenton | ||

− | + | = Publications = | |

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− | + | ''In Print'' | |

− | * | + | * [http://www.na-mic.org/publications/pages/display?search=MultiscaleShapeSegmentation&submit=Search&words=all&title=checked&keywords=checked&authors=checked&abstract=checked&searchbytag=checked&sponsors=checked| NA-MIC Publications Database on Multiscale Shape Segmentation Techniques] |

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− | [[:Category: | + | [[Category:Shape Analysis]] [[Category:Segmentation]] [[Category:MRI]] [[Category:Schizophrenia]] |

## Latest revision as of 00:58, 16 November 2013

Home < Projects:MultiscaleShapeSegmentationBack to NA-MIC Collaborations, Stony Brook University Algorithms, UNC Algorithms, GE Engineering, Kitware Engineering, Harvard DBP 1

# Multiscale Shape Segmentation

To represent multiscale variations in a shape population in order to drive the segmentation of deep brain structures, such as the caudate nucleus or the hippocampus.

# Description

## Shape Representation and Prior

The overview of our shape representation is given in Figure 1. Our technique defines a multiscale parametric model of surfaces belonging to the same population using a compact set of spherical wavelets targeted to that population (Figure 2). We further refine the shape representation by separating into groups wavelet coefficients that describe independent global and/or local biological variations in the population, using spectral graph partitioning. We then learn a prior probability distribution induced over each group to explicitly encode these variations at different scales and spatial locations (Figure 4) [1].

## Segmentation

Based on this representation, we derive a parametric active surfaceIn evolution using the multiscale prior coefficients as parameters for our optimization procedure to naturally include the prior for segmentation. Additionally, the optimization method can be applied in a coarse-to-fine manner.

## Results

We applied our algorithm to the caudate nucleus, a brain structure of interest in the study of schizophrenia [2]. Our validation shows our algorithm is computationally efficient and outperforms the Active Shape Model (ASM) algorithm, by capturing finer shape details.

# Key Investigators

- Georgia Tech Algorithms: Delphine Nain, Aaron Bobick, Allen Tannenbaum
- UNC Algorithms: Martin Styner
- GE Engineering: Jim Miller
- Kitware Engineering: Luis Ibanez
- Harvard DBP 1: Steven Haker, James Levitt, Marc Niethammer, Sylvain Bouix, Martha Shenton

# Publications

*In Print*