Projects:RegistrationLibrary:RegLib C15

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Slicer Registration Librar Case 15: Brain MR Alignment along AC-PC line

this is a set of reference landmarks. The transform is derived from these fiducials. lleft this is the moving image to which the calculated transform is applied. LEGEND

lleft this indicates the reference data that determines the transform.
lleft this indicates the moving image that is being realigned.

lleft Fiducials lleft T1 SPGR
2 points marking AC-PC line
3+ points marking midline
1 mm isotropic
256 x 256 x 116
RAS

Objective / Background

Keywords

MRI, brain, head, anterior commissure, posterior commissure, AC-PC Line, Talairach, fiducial alignment

Input Data

  • Button green moving white.jpg moving: T1 MPRAGE 1x1x1 mm voxel size

Registration Challenges

  • A dedicated module for AC-PC alignment is used.
  • the only difficulty lies with accurate placement of the AC-PC fiducials. Depending on image resolution and contrast these can be difficult to find.
  • midline fiducials should be easily obtainable from axial and coronal views. 3 midline fiducials suffice; more is recommended for a more robust solution.

Key Strategies

  • this is a special case of fiducial-based alignment. Instead of aligning two sets of fiducial pairs, only one set of fiducials is aligned with a predefined orientation: The plane defined by the midline fiducials is aligned to be vertical in coronal/axial views, and the line defined by the AC-PC line is rotated to be horizontal in a sagittal view.

Registration Results

original and aligned MRI

Download




Link to User Guide: How to Load/Save Registration Parameter Presets