Projects:RegistrationLibrary:RegLib C15

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v3.6.1 Slicer3-6Announcement-v1.png Slicer Registration Library Case #15:
Brain MR Alignment along AC-PC line

Input

[[Image::RegLib_C15_Fiducials.png|150px|lleft|this is the fixed reference image. All images are aligned into this space]] lleft this is the moving image. The transform is calculated by matching this to the reference image
fixed image/target moving image

Modules

Keywords

MRI, brain, head, anterior commissure, posterior commissure, AC-PC Line, Talairach, fiducial alignment

Input Data

  • Button green moving white.jpg moving: T1 MPRAGE 1x1x1 mm voxel size

Registration Challenges

  • A dedicated module for AC-PC alignment is used.
  • the only difficulty lies with accurate placement of the AC-PC fiducials. Depending on image resolution and contrast these can be difficult to find.
  • midline fiducials should be easily obtainable from axial and coronal views. 3 midline fiducials suffice; more is recommended for a more robust solution.

Key Strategies

  • this is a special case of fiducial-based alignment. Instead of aligning two sets of fiducial pairs, only one set of fiducials is aligned with a predefined orientation: The plane defined by the midline fiducials is aligned to be vertical in coronal/axial views, and the line defined by the AC-PC line is rotated to be horizontal in a sagittal view.

Registration Results

original and aligned MRI

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