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Group Study using the Tubular Surface Model

We have proposed a new framework for performing group studies on DW-MRI data using the Tubular Surface Model to study white-matter properties. We show that the model facilitates population studies by the natural registration that occurs by the sampling of WM properties along the fiber bundles center-lines. Further, by allowing us to characterize the discrimination ability of local regions of the fiber bundles, the framework allows us to identify the regions that are "affected" by the disorder under study. In our experiments, we have applied the framework to study the Cingulum Bundle towards discriminating Schizophrenia.