Mbirn: Ontology: Description of Development Plan

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  • Terms and relationships will include those already in UMLS and those that will be defined through BONFIRE, for a graphical interface (see Ontology: Project Background). Since the UMLS now automatically includes American Psychological Association (APA) Thesaurus terms ( http://www.apa.org/psycinfo/products/thesaurus.html as used in PsychInfo), we will not be adding any additional pre-existing data sources. Rather, through BONFIRE, we will create new terms and new relationships/links between terms that will transparently interact with the UMLS as needed.
  • Currently, most existing assessment terms in UMLS are not linked to cognitive or anatomical terms. Therefore, each assessment and subscore will be linked to basic cognitive functions and theoretical anatomical bases (where appropriate), with new relationships to be defined. For example, "California Verbal Learning Test" will be linked to "Learning" and "Memory."
  • “Missing” assessment names and acronyms (e.g., "CVLT" for "California Verbal Learning Test") will be “added” to our BONFIRE to provide unique IDs for each assessment and its subscores.
  • For the initial work, CFN will provide additional new terms and create new relationships via BONFIRE to test scope of ontology development.
  • BONFIRE options to define new terms and new relationships will be assigned to the User that defines the new information. This information will be stored in the User's "MyBONFIRE" database for the User's personal use; at the same time, this information also will be stored in an uncurated version of BONFIRE. Future curation processes will deem whether the new information is appropriate to add to the master, shared curated BONFIRE database.
  • Once this Ontology development work is underway, David Karger's (MIT) Haystack tool will provide an avenue to organize the user interface depending on specified relationships. BIRN would provide ontology information in OWL format to Haystack and the answer of how the data could be related and organized would come back in RDF format to the Mediator.

For more information see: